Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and
homeostasis. These modifications can promote, modulate and/or accelerate CKD and …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition
receptors, expressed primarily by myeloid cells. They recognize not only pathogen moieties …

Cardiovascular disease (CVD) and its complications are a leading cause of death
worldwide. Endothelial dysfunction plays a crucial role in the initiation and progression of …

Nonalcoholic fatty liver disease (NAFLD) is a pathology that contains a broad liver
dysfunctions spectrum. These alterations span from noninflammatory isolated steatosis until …

Alterations affecting high-density lipoproteins (HDLs) are one of the various abnormalities
observed in dyslipidemia in type 2 diabetes mellitus (T2DM) and obesity. Kinetic studies …

The blood-brain barrier (BBB), which consists mainly of brain microvascular endothelial cells
and astrocytes connected by tight junctions (TJs) and adhesion molecules (AMs), maintains …

Circulating apolipoprotein B-containing lipoproteins, notably the low-density lipoproteins,
enter the inner layer of the arterial wall, the intima, where a fraction of them is retained and …

Obesity and related metabolic syndromes have been recognized as important disease risks,
in which the role of adipokines cannot be ignored. Adiponectin (ADP) is one of the key …

Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …