[HTML][HTML] The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS

T McDonnell, C Wincup, I Buchholz, C Pericleous… - Blood reviews, 2020 - Elsevier
Abstract Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …

Oxidative post-translational modification of βeta 2-glycoprotein I in the pathophysiology of the anti-phospholipid syndrome

JC Weaver, SA Krilis, B Giannakopoulos - Free Radical Biology and …, 2018 - Elsevier
The anti-phospholipid syndrome (APS) is a prothrombotic autoimmune disorder
characterized by either thrombosis or pregnancy complications in the setting of persistent …

Metabarcoding Reveals Temporal Patterns of Community Composition and Realized Thermal Niches of Thalassiosira Spp. (Bacillariophyceae) from the Narragansett …

TA Rynearson, SA Flickinger, DN Fontaine - Biology, 2020 - mdpi.com
Diatoms generate nearly half of marine primary production and are comprised of a diverse
array of species that are often morphologically cryptic or difficult to identify using light …

Protein deimination and extracellular vesicle profiles in Antarctic seabirds

RA Phillips, I Kraev, S Lange - Biology, 2020 - mdpi.com
Pelagic seabirds are amongst the most threatened of all avian groups. They face a range of
immunological challenges which seem destined to increase due to environmental changes …

Beta-2-glycoprotein I as a biomarker for sepsis in critically ill patients in the intensive care unit: a prospective cohort study

IT Schrijver, H Kemperman, M Roest, J Kesecioglu… - Critical Care, 2020 - Springer
To the editor, It is difficult to diagnose sepsis in critically ill patients admitted to the intensive
care unit (ICU). A biomarker could help in sepsis identification and guide antibiotic use. A …

[HTML][HTML] Domain 5 of Beta 2 glycoprotein I: Friend or foe in health? Context matters

B Giannakopoulos, SA Krilis - Clinical Immunology, 2024 - Elsevier
Abstract Beta 2 glycoprotein I (B2GPI) is the major autoantigen in the antiphospholipid
syndrome, an autoimmune disorder characterized by thrombotic and obstetric complications …

The protective effect of apolipoprotein H in paediatric sepsis

Z Yu, C Xiao, R Liu, D Pi, B Jin, Z Zou, F Xu - Critical Care, 2024 - Springer
Background Sepsis is a severe condition characterized by acute organ dysfunction resulting
from an imbalanced host immune response to infections. Apolipoprotein H (APOH) is a …

Free thiol β2-GPI (β-2-Glycoprotein-I) provides a link between inflammation and oxidative stress in atherosclerotic coronary artery disease

JC Weaver, I Ullah, M Qi… - … and Vascular Biology, 2020 - Am Heart Assoc
Objective: Atherosclerotic coronary artery disease is well recognised as an inflammatory
disorder that is also influenced by oxidative stress. β2-GPI (β-2-glycoprotein-I) is a …

The secretome deregulations in a rat model of endotoxemic shock

A Blangy-Letheule, A Persello… - Oxidative Medicine …, 2021 - Wiley Online Library
Introduction. Septic shock is a systemic inflammatory response syndrome associated with
organ failures. Earlier clinical diagnosis would be of benefit to a decrease in the mortality …

Apolipoprotein H as a Crucial Immunomodulatory Factor in Sepsis

Z Yu, C Xiao, R Liu, D Pi, B Jin, Z Zou, F Xu - 2023 - researchsquare.com
Background. Sepsis is a life-threatening acute organ dysfunction caused by a dysregulated
immune response to infections. Apolipoprotein H (APOH) is an important plasma protein that …