CM López Mendoza… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy is one of the most widely used strategies to fight cancer, although it has disadvantages such as accumulation in healthy organs and lack of specificity by cancer cells …
MR Abolhassan, A Divsalar… - Journal of Molecular …, 2023 - Elsevier
Platinum-based complexes are effective chemotherapeutics which are applied in chemotherapy regimens to treat cancer. The present study is designed to investigate the …
O Abazari, Z Shafaei, A Divsalar… - Journal of the Iranian …, 2020 - Springer
In the present study, the interaction of the novel synthesized platinum complex named methyl-glycine 1, 10-phenanthroline platinum nitrate product with two most crucial blood …
The drug pharmacokinetics is affected upon binding with proteins, thus making drug-protein interactions crucial. This study investigated the interaction between enzalutamide and …
Hypochlorous acid (HOCl), an active bleaching agent is one of the major oxidant produced by neutrophils under physiological conditions. It is among one of the most potent reactive …
Alpha-2-macroglobulin is a multifunctional, highly abundant, plasma protein which reacts with a wide variety of molecules and drugs including cisplatin. Cisplatin is commonly used …
Methotrexate (MTX) is advised in the treatment of solid tumours, hematologic malignancies and autoimmune disorders. On reaching the circulation, 60% of MTX is bound to the proteins …
B Yang, R Kou, H Wang, A Wang… - International …, 2024 - spandidos-publications.com
Globally, non-small cell lung cancer (NSCLC) is a significant threat to human health, and constitutes> 80% of lung cancer cases. Cisplatin (CDDP), a commonly used drug in clinical …
VI Raskolupova, TV Popova, OD Zakharova… - Molecules, 2021 - mdpi.com
BODIPY dyes are photostable neutral derivatives of 4, 4-difluoro-4-bora-3a, 4a-diaza-s- indacene. These are widely used as chemosensors, laser materials, and molecular probes …