Endometrial immune dysfunction in recurrent pregnancy loss

C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

The update immune-regulatory role of pro-and anti-inflammatory cytokines in recurrent pregnancy losses

X Yang, Y Tian, L Zheng, T Luu… - International journal of …, 2022 - mdpi.com
Recurrent pregnancy losses (RPL) is a common reproductive disorder with various
underlying etiologies. In recent years, rapid progress has been made in exploring the …

Maternal IL-33 critically regulates tissue remodeling and type 2 immune responses in the uterus during early pregnancy in mice

N Valero-Pacheco, EK Tang, N Massri… - Proceedings of the …, 2022 - National Acad Sciences
The pregnant uterus is an immunologically rich organ, with dynamic changes in the
inflammatory milieu and immune cell function underlying key stages of pregnancy. Recent …

[HTML][HTML] Immunologic insights in recurrent spontaneous abortion: Molecular mechanisms and therapeutic interventions

D Guan, W Sun, M Gao, Z Chen, X Ma - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Recurrent spontaneous abortion refers to the occurrence of two or more spontaneous
abortions before or during the early stages of pregnancy. The immune system plays a crucial …

[HTML][HTML] Evaluation of Th17 and Treg cytokines in patients with unexplained recurrent pregnancy loss

M Farshchi, E Abdollahi, N Saghafi… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
Methods: Samples were extracted from the peripheral blood, endocervix, endometrium, and
vagina of 14 patients with URPL and 12 normal non-pregnant women as a control (normal) …

Development and utilization of human decidualization reporter cell line uncovers new modulators of female fertility

M Haller, Y Yin, L Ma - … of the National Academy of Sciences, 2019 - National Acad Sciences
Failure of embryo implantation accounts for a significant percentage of female infertility.
Exquisitely coordinated molecular programs govern the interaction between the competent …

Expression of IL-33 receptor is significantly up-regulated in B cells during pregnancy and in the acute phase of preterm birth in mice

N Valeff, L Juriol, F Quadrana, DO Muzzio… - Frontiers in …, 2020 - frontiersin.org
Interleukin-33 (IL-33) is a mucosal alarmin belonging to the IL-1 cytokine family and is now
recognized to have a key role in innate and adaptive immunity, contributing to tissue …

Association of FOXP3 rs3761548 polymorphism and its reduced expression with unexplained recurrent spontaneous abortions: A South Indian study

K Dirsipam, D Ponnala, D Madduru… - American Journal of …, 2021 - Wiley Online Library
Abstract Problem: Fork Head Box Protein 3 (FOXP3) is an X‐linked gene, codes for a master
transcription regulatory protein that controls the development and function of …

IL-33 and soluble ST2 in follicular fluid are associated with premature ovarian insufficiency

M Tang, X Sun, P Li, W Deng, X Zhan, P Sun… - Frontiers in …, 2024 - frontiersin.org
Background Premature ovarian insufficiency (POI) is a common reproductive disease that is
associated with chronic inflammation in ovaries. Interleukin 33 (IL-33) is a pro-inflammatory …

Association between IL-33 gene polymorphism (Rs7044343) and risk of allergic rhinitis

S Falahi, SHR Mortazavi, F Salari… - Immunological …, 2022 - Taylor & Francis
Background Allergic rhinitis (AR) is a T helper type 2 (Th2)-mediated upper airways disease
in which genetics factors including cytokine genes play a prominent role. Interleukin-33 (IL …