For many cancer types, cancer cells invade into surrounding tissues by collective movement
of cell groups that remain connected via cell–cell junctions. This migration is completely …

Planar polarity is a developmental mechanism wherein individual cell behaviors are
coordinated across a two-dimensional plane. A great deal of attention has been paid to the …

Sequential developmental events, starting from the moment of fertilization, are crucial for the
acquisition of animal body plan. Subtle modifications in such early events are likely to have …

Smokeless tobacco products provide an alternative to cigarettes; however, smokeless
tobacco is carcinogenic and harmful to human health. This study evaluated the toxicological …

Cigarette smoke significantly induces oxidative stress, resulting in cardiovascular disease.
NRF2, a well-known antioxidative stress response factor, is generally considered to play …

Cell migration is key to many physiological and pathological conditions, including cancer
metastasis. The cellular and molecular bases of cell migration have been thoroughly …

Embryonic cell fate specification and axis patterning requires integration of several signaling
pathways that orchestrate region-specific gene expression. The transcription factor signal …

In animals the basic body plan is determined at early stages of embryogenesis. In fish and
amphibians dorso-ventral polarity is established by maternal factors present in the oocyte …

Fibulin-4 is an extracellular matrix protein required for the formation of the elastic fibers.
Human mutations in the fibulin-4 gene cause autosomal recessive cutis laxa with …