[HTML][HTML] The characteristics and clinical significance of atypical mitosis in breast cancer

A Lashen, MS Toss, M Alsaleem, AR Green… - Modern Pathology, 2022 - Elsevier
Atypical mitosis is considered a feature of malignancy, however, its significance in breast
cancer (BC) remains elusive. Here, we aimed to assess the clinical value of atypical mitoses …

Re-evaluation of publicly available gene-expression databases using machine-learning yields a maximum prognostic power in breast cancer

D Tschodu, J Lippoldt, P Gottheil, AS Wegscheider… - Scientific Reports, 2023 - nature.com
Gene expression signatures refer to patterns of gene activities and are used to classify
different types of cancer, determine prognosis, and guide treatment decisions …

CD301 and LSECtin glycan-binding receptors of innate immune cells serve as prognostic markers and potential predictors of immune response in breast cancer …

AS Wegscheider, I Wojahn, P Gottheil, M Spohn… - …, 2024 - academic.oup.com
Glycosylation is a prominent posttranslational modification, and alterations in glycosylation
are a hallmark of cancer. Glycan-binding receptors, primarily expressed on immune cells …

Classification and prediction for multi-cancer data with ultrahigh-dimensional gene expressions

LP Chen - Plos one, 2022 - journals.plos.org
Analysis of gene expression data is an attractive topic in the field of bioinformatics, and a
typical application is to classify and predict individuals' diseases or tumors by treating gene …

Molecular phenotyping of malignant canine mammary tumours: Detection of high‐risk group and its relationship with clinicomolecular characteristics

M Zamani‐Ahmadmahmudi, M Jajarmi… - Veterinary and …, 2023 - Wiley Online Library
Canine mammary gland tumours (CMTs) constitute the most common cancer in female dogs
and comprise approximately 50% of all canine cancers. With the advent of high‐throughput …

[PDF][PDF] Identification of lipid droplet-associated genes in breast cancer patients

S Dogan, J Leopold, DT Hoffmann, H Kubitschke… - 2022 - scholar.archive.org
Background: Abnormal lipid metabolism plays an essential role in breast cancer progression
and metastasis. Lipid droplets (LD) have multifunctional tasks as they store and transfer …

Prognostic relevance of gene-expression signatures

D Tschodu, J Lippoldt, P Gottheil… - arXiv preprint arXiv …, 2022 - arxiv.org
Cancer prognosis can be regarded as estimating the risk of future outcomes from multiple
variables. In prognostic signatures, these variables represent expressions of genes that are …

Gene Screening in High-Throughput Right-Censored Lung Cancer Data

C Ke, D Bandyopadhyay, M Acunzo, R Winn - Onco, 2022 - mdpi.com
Background: Advances in sequencing technologies have allowed collection of massive
genome-wide information that substantially advances lung cancer diagnosis and prognosis …

[HTML][HTML] Identification of Lipid Droplet-Associated Genes in Breast Cancer Patients

S Dogan, J Leopold, DT Hoffmann, H Kubitschke… - Lipidology, 2024 - mdpi.com
Lipid droplets (LDs) are known to be involved in the invasion and migration of breast cancer
(BC) cells. This study aimed to identify LD-associated genes as prognostic markers in BC …

Prognostic value of deep learning based mitotic count in hormonal receptor-and HER2-positive breast cancer

M Balkenhol, C Mercan, L Tessier, D Tellez, R Salgado… - 2023 - researchsquare.com
The discovery of molecular subtypes has corroborated the heterogeneity of breast cancers.
But in clinical routine, treatment selection relies on measuring the aggressiveness of the …