Antioxidant therapeutic strategies in neurodegenerative diseases

C Morén, RM deSouza, DM Giraldo, C Uff - International journal of …, 2022 - mdpi.com
The distinguishing pathogenic features of neurodegenerative diseases include
mitochondrial dysfunction and derived reactive oxygen species generation. The neural …

Pharmacological and non‐pharmacological interventions to enhance sleep in mild cognitive impairment and mild Alzheimer's disease: A systematic review

J Blackman, M Swirski, J Clynes… - Journal of sleep …, 2021 - Wiley Online Library
Suboptimal sleep causes cognitive decline and probably accelerates Alzheimer's Disease
(AD) progression. Several sleep interventions have been tested in established AD dementia …

Multimodal smart eyewear for longitudinal eye movement tracking

SZ Homayounfar, S Rostaminia, A Kiaghadi, X Chen… - Matter, 2020 - cell.com
Contextual measurements of multiple physiological signals using familiar garments or
accessories can provide insights into health and behavior. Recording these signals on or …

Associations of sleep disorders with all-cause MCI/dementia and different types of dementia–clinical evidence, potential pathomechanisms and treatment options: A …

G Mayer, H Frohnhofen, M Jokisch… - Frontiers in …, 2024 - frontiersin.org
Due to worldwide demographic change, the number of older persons in the population is
increasing. Aging is accompanied by changes of sleep structure, deposition of beta-amyloid …

Resistance and resilience to Alzheimer's disease

CS Latimer, KE Prater… - Cold Spring …, 2024 - perspectivesinmedicine.cshlp.org
Dementia is a significant public health crisis; the most common underlying cause of age-
related cognitive decline and dementia is Alzheimer's disease neuropathologic change …

Radiooculogram (ROG) for eye movement sensing with eyes closed

Z Zhang, EC Kan - 2022 IEEE Sensors, 2022 - ieeexplore.ieee.org
This paper presents radiooculogram (ROG), a novel sensor for non-invasive eye movement
(EM) monitoring with eyes closed. We have experimentally demonstrated accurate …

Deregulation of Melatonin Receptors and Differential Modulation of After‐Hyperpolarization and Ih Currents Using Melatonin Treatment Due to Amyloid‐β‐Induced …

MJ Eslamizade, F Saffarzadeh… - Cell Biochemistry …, 2024 - Wiley Online Library
Treatment with melatonin is routinely prescribed for its potent antioxidant and cognitive‐
promoting effects, nevertheless, it has yet to find neuromodulatory effects in normal and …

EEG coherence and power spectra during REM sleep related to melatonin intake in mild-to-moderate Alzheimer's disease: a pilot study

MA Cruz-Aguilar, I Ramírez-Salado… - International Journal …, 2023 - Taylor & Francis
Introduction: It has been reported that melatonin diminishes rapid eye movement (REM)
sleep latency in patients with Alzheimer's disease (AD). Pharmacological studies suggest …

Melatonin and Inflammatory and Immune-Modulated Diseases: New Applications of a Metabolite Also Produced by Plants

LF Laurindo, B de Oliveira Zanuso, EL Guiguer… - Plant Specialized …, 2024 - Springer
Melatonin (MT) from plant species has attracted attention in the past decade. It is still the
only conserved molecule that is broad spectrum as a regulator of biological functions since it …

Progress in the causes of sleep disorders during the early-stage Alzheimer's disease

Y Li, Z Li, Y Wang - E3S Web of Conferences, 2024 - e3s-conferences.org
The most prevalent chronic disease among senior people, and its prevalence rises with age,
is Alzheimer's disease (AD). One study predicts that the prevalence of dementia will triple …