COVID‐19 in children. II: Pathogenesis, disease spectrum and management

AR Howard‐Jones, DP Burgner… - … of paediatrics and …, 2022 - Wiley Online Library
The global disruption of the COVID‐19 pandemic has impacted the life of every child either
directly or indirectly. This review explores the pathophysiology, immune response, clinical …

Which children and young people are at higher risk of severe disease and death after hospitalisation with SARS-CoV-2 infection in children and young people: A …

R Harwood, H Yan, NT Da Camara, C Smith… - …, 2022 - thelancet.com
Background We aimed to describe pre-existing factors associated with severe disease,
primarily admission to critical care, and death secondary to SARS-CoV-2 infection in …

Global characteristics and outcomes of SARS-CoV-2 infection in children and adolescents with cancer (GRCCC): a cohort study

S Mukkada, N Bhakta, GL Chantada, Y Chen… - The Lancet …, 2021 - thelancet.com
Background Previous studies have shown that children and adolescents with COVID-19
generally have mild disease. Children and adolescents with cancer, however, can have …

[HTML][HTML] COVID-19 in immunocompromised populations: implications for prognosis and repurposing of immunotherapies

JD Goldman, PC Robinson, TS Uldrick… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. COVID-19 has highly
variable disease severity and a bimodal course characterized by acute respiratory viral …

Risk factors for severe COVID-19 in hospitalized children in Canada: A national prospective study from March 2020–May 2021

DS Farrar, O Drouin, CM Hepburn, K Baerg… - The Lancet Regional …, 2022 - thelancet.com
Background Children living with chronic comorbid conditions are at increased risk for severe
COVID-19, though there is limited evidence regarding the risks associated with specific …

[HTML][HTML] SARS-CoV-2 in children with cancer or after haematopoietic stem cell transplant: an analysis of 131 patients

GM Haeusler, RA Ammann, F Carlesse, AH Groll… - European journal of …, 2021 - Elsevier
Purpose There are limited data on SARS-CoV-2 (COVID-19) infection in children with
cancer or after haematopoietic stem cell transplant (HSCT). We describe the severity and …

COVID-19 in immunosuppressed children

E Nicastro, L Verdoni, LR Bettini, G Zuin… - Frontiers in …, 2021 - frontiersin.org
Following the spread of the SARS-CoV-2 infection and coronavirus disease 2019 (COVID-
19) to a global pandemic, concerns have arisen for the disease impact in at-risk populations …

SARS-CoV-2 in pediatric cancer: a systematic review

S Schlage, T Lehrnbecher, R Berner, A Simon… - European Journal of …, 2022 - Springer
The outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
in December 2019 in Wuhan challenges pediatric oncologists in an unexpected way. We …

SARS-CoV-2 in childhood cancer in 2020: a disease of disparities

EE Johnston, I Martinez, ES Davis, C Caudill… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE The Pediatric Oncology COVID-19 Case Report registry supplies pediatric
oncologists with data surrounding the clinical course and outcomes in children with cancer …

Updated guidance on use and prioritization of monoclonal antibody therapy for treatment of COVID-19 in adolescents

J Wolf, MJ Abzug, BI Anosike, SB Vora… - Journal of the …, 2022 - academic.oup.com
Abstract Background Starting in November 2020, the US Food and Drug Administration
(FDA) has issued Emergency Use Authorizations (EUAs) for multiple novel virus-neutralizing …