[HTML][HTML] Role and mechanism of gut microbiota in human disease

Y Chen, J Zhou, L Wang - Frontiers in cellular and infection …, 2021 - frontiersin.org
The human gut microbiome is a huge microbial community that plays an irreplaceable role
in human life. With the further development of research, the influence of intestinal flora on …

Interaction between the microbiota, epithelia, and immune cells in the intestine

H Kayama, R Okumura, K Takeda - Annual review of …, 2020 - annualreviews.org
The gastrointestinal tract harbors numerous commensal bacteria, referred to as the
microbiota, that benefit host health by digesting dietary components and eliminating …

Fecal microbiota transplantation protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 …

Z Zhao, J Ning, X Bao, M Shang, J Ma, G Li, D Zhang - Microbiome, 2021 - Springer
Background Parkinson's disease (PD) is a prevalent neurodegenerative disorder, displaying
not only well-known motor deficits but also gastrointestinal dysfunctions. Consistently, it has …

The potential role of gut microbiota in Alzheimer's disease: from diagnosis to treatment

A Varesi, E Pierella, M Romeo, GB Piccini, C Alfano… - Nutrients, 2022 - mdpi.com
Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …

The role of gut dysbiosis in Parkinson's disease: mechanistic insights and therapeutic options

Q Wang, Y Luo, K Ray Chaudhuri, R Reynolds, EK Tan… - Brain, 2021 - academic.oup.com
Parkinson's disease is a common neurodegenerative disorder in which gastrointestinal
symptoms may appear prior to motor symptoms. The gut microbiota of patients with …

Role of microbiota-gut-brain axis in regulating dopaminergic signaling

S Hamamah, A Aghazarian, A Nazaryan, A Hajnal… - Biomedicines, 2022 - mdpi.com
Dopamine is a neurotransmitter that plays a critical role both peripherally and centrally in
vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and …

The influence of gut dysbiosis in the pathogenesis and management of ischemic stroke

SB Chidambaram, AG Rathipriya, AM Mahalakshmi… - Cells, 2022 - mdpi.com
Recent research on the gut microbiome has revealed the influence of gut microbiota (GM)
on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity …

The gut–brain axis and its relation to Parkinson's disease: a review

EM Klann, U Dissanayake, A Gurrala… - Frontiers in aging …, 2022 - frontiersin.org
Parkinson's disease is a chronic neurodegenerative disease characterized by the
accumulation of misfolded alpha-synuclein protein (Lewy bodies) in dopaminergic neurons …

Gut bacterial profiles in Parkinson's disease: A systematic review

Z Li, H Liang, Y Hu, L Lu, C Zheng… - CNS neuroscience & …, 2023 - Wiley Online Library
Introduction Recent advances have highlighted the relationships between gut dysbiosis and
Parkinson's disease (PD). Microbiota transplantation from PD patients to mice can induce …

The association between early-life gut microbiota and long-term health and diseases

A Sarkar, JY Yoo, S Valeria Ozorio Dutra… - Journal of clinical …, 2021 - mdpi.com
Early life gut microbiota have been increasingly recognized as major contributors to short
and/or long-term human health and diseases. Numerous studies have demonstrated that …