Progress in modelling of brain dynamics during anaesthesia and the role of sleep-wake circuitry

G Nguyen, S Postnova - Biochemical pharmacology, 2021 - Elsevier
General anaesthesia is used widely in surgery and during interventional medical
procedures, but little is known about the exact neural mechanisms for how unconsciousness …

[HTML][HTML] Cortical waste clearance in normal and restricted sleep with potential runaway tau buildup in Alzheimer's disease

T Tekieh, PA Robinson, S Postnova - Scientific Reports, 2022 - nature.com
Accumulation of waste in cortical tissue and glymphatic waste clearance via extracellular
voids partly drives the sleep-wake cycle and modeling has reproduced much of its …

[HTML][HTML] Sleep as a random walk: A super-statistical analysis of EEG data across sleep stages

C Metzner, A Schilling, M Traxdorf, H Schulze… - Communications …, 2021 - nature.com
In clinical practice, human sleep is classified into stages, each associated with different
levels of muscular activity and marked by characteristic patterns in the EEG signals. It is …

Pilot feasibility testing of biomathematical model recommendations for personalising sleep timing in shift workers

P Varma, S Postnova, AJK Phillips… - Journal of Sleep …, 2023 - Wiley Online Library
Sleep disturbances and circadian disruption play a central role in adverse health, safety,
and performance outcomes in shift workers. While biomathematical models of sleep and …

[HTML][HTML] Personalized sleep-wake patterns aligned with circadian rhythm relieve daytime sleepiness

J Hong, SJ Choi, SH Park, H Hong, V Booth, EY Joo… - Iscience, 2021 - cell.com
Shift workers and many other groups experience irregular sleep-wake patterns. This can
induce excessive daytime sleepiness that decreases productivity and elevates the risk of …

Prediction of shiftworker alertness, sleep, and circadian phase using a model of arousal dynamics constrained by shift schedules and light exposure

SA Knock, M Magee, JE Stone, S Ganesan, MD Mulhall… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives The study aimed to, for the first time,(1) compare sleep, circadian
phase, and alertness of intensive care unit (ICU) nurses working rotating shifts with those …

Desynchrony and synchronisation underpinning sleep–wake cycles

DE Postnov, KO Merkulova… - The European Physical …, 2021 - epjplus.epj.org
This paper studies mechanisms of synchronisation and loss of synchrony among the three
key oscillatory processes controlling sleep–wake cycles in the human brain: the 24-h …

Investigating the effects of psychoactive substances on subsequent sleep

C Gardiner - 2024 - acuresearchbank.acu.edu.au
Sleep is essential for health and wellbeing. However, it is estimated that up to 40% of the
population fail to attain the recommended seven to nine hours of sleep per night. A key …

Altered Coactive Micropattern Connectivity in the Default‐Mode Network during the Sleep‐Wake Cycle

Y Cui, Q Chen, Y Xia, Z Wang, Y Guo, G Zhang… - Neural …, 2020 - Wiley Online Library
The default‐mode network (DMN) is believed to be associated with levels of consciousness,
but how the functional connectivity (FC) of the DMN changes across different states of …

Circadian rhythm and mental health relationships among nurses working night shifts in the era of COVID-19 pandemic

CE Okechukwu - 2023 - iris.uniroma1.it
In tutto il mondo, molti infermieri lavorano durante la notte a rotazione o tempo
indeterminato. Per migliorare l'allocazione del personale infermieristico, ridurre il carico di …