Advances in acute ischemic stroke therapy

Y Xiong, AK Wakhloo, M Fisher - Circulation research, 2022 - Am Heart Assoc
The treatment of acute ischemic stroke continues to advance. The mainstay of treatment
remains intravenous thrombolysis with alteplase. Recent studies demonstrated that later …

Endovascular management of acute stroke

TN Nguyen, M Abdalkader, U Fischer, Z Qiu, S Nagel… - The Lancet, 2024 - thelancet.com
Stroke related to large vessel occlusion is a leading cause of disability and death worldwide.
Advances in endovascular therapy to reopen occluded arteries have been shown to reduce …

No-reflow phenomenon in stroke patients: a systematic literature review and meta-analysis of clinical data

A Mujanovic, F Ng, TR Meinel… - … Journal of Stroke, 2024 - journals.sagepub.com
Background: The no-reflow phenomenon refers to the absence of microvascular reperfusion
despite macrovascular reperfusion. Aim: The aim of this analysis was to summarize the …

Imaging biomarkers for clinical applications in neuro-oncology: current status and future perspectives

FY Chiu, Y Yen - Biomarker Research, 2023 - Springer
Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …

Overview of imaging modalities in stroke

AL Czap, SA Sheth - Neurology, 2021 - AAN Enterprises
Purpose of the Review This article reviews common imaging modalities used in diagnosis
and management of acute stroke. Each modality is discussed individually and clinical …

[HTML][HTML] Ischemic core overestimation on computed tomography perfusion

Á García-Tornel, D Campos, M Rubiera, S Boned… - Stroke, 2021 - journals.lww.com
Background and Purpose: Different studies have pointed that CT perfusion (CTP) could
overestimate ischemic core in early time window. We aim to evaluate the influence of time …

Improvement of automatic ischemic stroke lesion segmentation in CT perfusion maps using a learned deep neural network

M Soltanpour, R Greiner, P Boulanger… - Computers in biology and …, 2021 - Elsevier
Acute ischemic stroke is one of the leading causes of death and long-term disability
worldwide. It occurs when a blood clot blocks an artery that supplies blood to the brain …

Perfusion imaging predicts short‐term clinical outcome in isolated posterior cerebral artery occlusion stroke

HA Salim, S Huang, DA Lakhani, J Mei… - Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Ischemic strokes due to isolated posterior cerebral artery
(PCA) occlusions represent 5% of all strokes but have significant impacts on patients' quality …

Perfusion abnormalities on 24-hour perfusion imaging in patients with complete endovascular reperfusion

A Mujanovic, A Imhof, S Zheng, EI Piechowiak… - Stroke, 2024 - ahajournals.org
BACKGROUND: Perfusion abnormalities in the infarct and salvaged penumbra have been
proposed as a potential reason for poor clinical outcome (modified Rankin Scale score> 2) …

Predicting treatment-specific lesion outcomes in acute ischemic stroke from 4D CT perfusion imaging using spatio-temporal convolutional neural networks

K Amador, M Wilms, A Winder, J Fiehler… - Medical Image Analysis, 2022 - Elsevier
For the diagnosis and precise treatment of acute ischemic stroke, predicting the final location
and volume of lesions is of great clinical interest. Current deep learning-based prediction …