Objective To understand the role of the genetic changes and bone marrow
microenvironment on the development, progression, and staging of multiple myeloma (MM) …

Obesity is a global pandemic that has been associated with the development of breast,
endometrial, large intestine, renal, esophageal, and pancreatic cancer. Obesity is also …

Objective The purpose of this article is to review the association of the obesity pandemic with
appearance of cancers in young adults under age 50 and to define potential mechanisms by …

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant clonal
disorder that progresses to multiple myeloma (MM), or other plasma-cell or lymphoid …

Background Obesity is the only known modifiable multiple myeloma (MM) risk factor.
However, the influence of obesity in earlier or later adulthood and the role of other energy …

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant condition
of multiple myeloma with few known risk factors. The emergence of mass spectrometry (MS) …

Multiple myeloma is a plasma cell skeletal malignancy. While therapeutic agents such as
bortezomib and lenalidomide have significantly improved overall survival, the disease is …

Multiple myeloma (MM) is the second-most-common hematologic malignancy and the most
frequent cancer to involve bone. MM bone disease (MMBD) has devastating consequences …

The etiology of multiple myeloma (MM) is poorly understood. Summary data from genome-
wide association studies (GWASs) of multiple phenotypes can be exploited in a Mendelian …

Background Multiple myeloma is one of the most common haematological malignancies in
the USA and is consistently preceded by monoclonal gammopathy of undetermined …