Allergic rhinitis is clinically defined as a symptomatic disorder of the nose induced by an IgE-
mediated inflammation after allergen exposure of the membranes lining the nose. Symptoms …

Background Allergic rhinitis (AR) is an inflammatory disease of the nasal mucosa impacting
up to 25% of Canadians. The standard of care for AR includes a treatment plan that takes …

Objective Allergic rhinitis (AR) is one of the most common diseases affecting adults. It is the
most common chronic disease in children in the United States today and the fifth most …

Second-generation histamine H 1 receptor antagonists (antihistamines) have been
developed to reduce or eliminate the sedation and anticholinergic adverse effects that occur …

Fexofenadine, the active metabolite of terfenadine, is a selective histamine Hi receptor
antagonist that does not cross the blood brain barrier and appears to display some anti …

The recently introduced H 1 receptor antagonists ebastine, fexofenadine and mizolastine,
and the relatively new H 1 antagonists acrivastine, astemizole, azelastine, cetirizine …

Antihistamines are useful medications for the treatment of a variety of allergic disorders.
Second-generation antihistamines avidly and selectively bind to peripheral histamine H 1 …

Antihistamines are effective medications that have been used for decades in the
management of allergic rhinitis; however, they may be administered or selected in an …

Background The objective of this study was to determine the onset of action of azelastine
hydrochloride nasal spray compared with placebo and an intranasal steroid, mometasone …

Second generation antihistamines are recognised as being highly effective treatments for
allergy-based disease and are among the most frequently prescribed and safest drugs in the …