[HTML][HTML] Cholesterol metabolism, pancreatic β-cell function and diabetes

C Perego, L Da Dalt, A Pirillo, A Galli… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Cholesterol plays an essential role in determining cell membrane physico-chemical
characteristics and functions. A proper membrane structure is critical in pancreatic β-cells for …

Diabetogenic action of statins: mechanisms

R Carmena, DJ Betteridge - Current atherosclerosis reports, 2019 - Springer
Abstract Purpose of Review Observational studies and meta-analyses of randomized clinical
trials data have revealed a 10–12% increased risk of new-onset diabetes (NOD) associated …

[HTML][HTML] Editor's choice--European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of asymptomatic lower limb peripheral …

J Nordanstig, CA Behrendt, I Baumgartner… - European Journal of …, 2024 - Elsevier
BIOTRONIK's First in Man study of the Passeo-18 LUX drug releasing PTA Balloon Catheter
vs. the uncoated Passeo-18 PTA balloon catheter in subjects requiring revascularisation of …

[HTML][HTML] Pyrroloquinoline-quinone to reduce fat accumulation and ameliorate obesity progression

NS Mohamad Ishak, K Ikemoto - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Obesity is a major health concern worldwide, and its prevalence continues to increase in
several countries. Pyrroloquinoline quinone (PQQ) is naturally found in some foods and is …

Efficacy and safety of PCSK9 monoclonal antibodies in patients with Diabetes

BH Marouf, Z Iqbal, JB Mohamad, B Bashir… - Clinical Therapeutics, 2022 - Elsevier
Purpose Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are novel drugs
that have proven efficacy in improving cardiovascular outcomes. Roles for the PCSK9 …

[HTML][HTML] Do statins counteract the effect of antidiabetic drugs? Results of the SCEAD study

BA Tarim, F Fici, I Tengiz, S Avunduk… - Yonsei Medical …, 2023 - ncbi.nlm.nih.gov
Purpose Diabetes and dyslipidemia are leading causes of mortality and morbidity.
According to international guidelines, statins are the cornerstone of treatment in patients with …

[HTML][HTML] Efficacy and safety of bempedoic acid in patients with and without metabolic syndrome: Pooled analysis of data from four phase 3 clinical trials

MD Shapiro, PR Taub, MJ Louie, L Lei, CM Ballantyne - Atherosclerosis, 2023 - Elsevier
Background and aims Bempedoic acid significantly lowers low-density lipoprotein
cholesterol (LDL-C) in patients with hypercholesterolemia but its effects in patients with …

[HTML][HTML] New opportunities for lowering low-density lipoprotein cholesterol: comparative characteristics of PCSK9-targeted therapy

SK Zyryanov, OI Butranova - Russian Journal of Cardiology, 2022 - russjcardiol.elpub.ru
The spread of cardiovascular diseases has the nature of an epidemic, which is enhanced by
lipid profile disorders, manifested by hypercholesterolemia. Numerous conventional …

[HTML][HTML] Новые возможности снижения уровня холестерина липопротеидов низкой плотности: сравнительные характеристики PCSK9-таргетной терапии

СК Зырянов, ОИ Бутранова - Российский кардиологический …, 2022 - cyberleninka.ru
Распространение сердечно-сосудистых заболеваний носит характер эпидемии, в
основе которой лежат нарушения липидного профиля, проявляющиеся …

Supplementation of pyrroloquinoline quinone with atorvastatin augments mitochondrial biogenesis and attenuates low grade inflammation in obese rats

K Devasani, R Kaul, A Majumdar - European Journal of Pharmacology, 2020 - Elsevier
Mitochondrial dysfunction and Inflammation play a significant role in the manifestation of the
co-morbidities of obesity. The study deciphered the impact of Pyrroloquinoline quinone …