Autoantibodies to synaptic receptors and neuronal cell surface proteins in autoimmune diseases of the central nervous system
J Dalmau, C Geis, F Graus - Physiological reviews, 2017 - journals.physiology.org
Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …
Identification of common genetic risk variants for autism spectrum disorder
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Neuropathological criteria of anti-IgLON5-related tauopathy
E Gelpi, R Höftberger, F Graus, H Ling, JL Holton… - Acta …, 2016 - Springer
We recently reported a novel neurological syndrome characterized by a unique NREM and
REM parasomnia with sleep apnea and stridor, accompanied by bulbar dysfunction and …
REM parasomnia with sleep apnea and stridor, accompanied by bulbar dysfunction and …
A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series …
L Sabater, C Gaig, E Gelpi, L Bataller… - The Lancet …, 2014 - thelancet.com
Background Autoimmunity might be associated with or implicated in sleep and
neurodegenerative disorders. We aimed to describe the features of a novel neurological …
neurodegenerative disorders. We aimed to describe the features of a novel neurological …
Anti-IgLON 5 Disease
A Heidbreder, K Philipp - Current Treatment Options in Neurology, 2018 - Springer
Purpose of review This review aims to give an overview about the current knowledge of this
novel neurological disorder associated to IgLON-5 antibodies and its treatment. Recent …
novel neurological disorder associated to IgLON-5 antibodies and its treatment. Recent …
Common risk variants identified in autism spectrum disorder
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
Cellular investigations with human antibodies associated with the anti-IgLON5 syndrome
Abstract Background Antibodies against IgLON5, a neuronal adhesion protein of unknown
function, are markers of a novel neurological disorder termed anti-IgLON5 syndrome. The …
function, are markers of a novel neurological disorder termed anti-IgLON5 syndrome. The …
Negr1 controls adult hippocampal neurogenesis and affective behaviors
Recent genome-wide association studies on major depressive disorder have implicated
neuronal growth regulator 1 (Negr1), a GPI-anchored cell adhesion molecule in the …
neuronal growth regulator 1 (Negr1), a GPI-anchored cell adhesion molecule in the …
Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology
F Bernhard, K Landgraf, N Klöting, A Berthold… - Diabetologia, 2013 - Springer
Aims/hypothesis Genome-wide association studies (GWAS) have identified numerous single-
nucleotide polymorphisms associated with obesity, consequently implying a role in …
nucleotide polymorphisms associated with obesity, consequently implying a role in …