Recent years have seen an increasing emphasis on foods and food components in disease
prevention. Garlic (Allium sativum L.), one of the best-researched herbal remedies, holds a …

Despite its complex pharmacokinetic and pharmacodynamic profile, warfarin is still one of
the most widely used oral anticoagulant agents. Attaining optimal anticoagulation with this …

Objectives The therapeutic use of nutrient-based 'nutraceuticals' and plant-based
'phytoceuticals' for the treatment of mental disorders is common; however, despite recent …

Interest and information in the field of medical toxicology has grown rapidly, but there has
never been a concise, authoritative reference focused on the subjects of natural substances …

Background and Aim: Alternative treatments for respiratory disorders attempt to prevent or
relieve symptoms and enhance functions. Furthermore, substantial evidence shows that …

Background and purpose: Patients commonly take complementary medicines in conjunction
with warfarin yet evidence supporting the safety or the risk of a herb–drug interaction is …

Devil's claw (Harpagophytum spp., Pedaliaceae) is one of the best-documented
phytomedicines. Its mode of action is largely elucidated, and its efficacy and excellent safety …

Study Objective. To determine the risk of bleeding and supratherapeutic international
normalized ratios (INRs) associated with use of complementary and alternative medicine …

Objectives The aim of this study was to systematically review data regarding
pharmacokinetic (PK)-pharmacodynamic (PD) parameters from randomized controlled trials …

A plethora of active compounds found in herbal medicines can serve as substrate for
enzymes involved in the metabolism of xenobiotics. When a medicinal plant is co …