Menopause is often a turning point for women's health worldwide. Increasing knowledge
from experimental data and clinical studies indicates that cardiometabolic changes can …

Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Alzheimer's disease has a higher incidence in older women, with a spike in cognitive
decline that tracks with visceral adiposity, dysregulated energy homeostasis and bone loss …

BACKGROUND. The relation between the menopause transition (MT) and changes in body
composition or weight remains uncertain. We hypothesized that, independent of …

Accumulating evidence suggests that the gut microbiota regulates obesity through
metabolite-host interactions. However, the mechanisms underlying such interactions have …

Every year, 2 million women reach menopause in the United States, and they may spend
40% or more of their life in a postmenopausal state. In the years immediately preceding …

Metabolic syndrome, variously known also as syndrome X, insulin resistance, etc., is defined
by WHO as a pathologic condition characterized by abdominal obesity, insulin resistance …

Multiple changes occur across various endocrine systems as an individual ages. The
understanding of the factors that cause age-related changes and how they should be …

The activity of 5′-adenosine monophosphate-activated protein kinase (AMPK) is inversely
correlated with the cellular availability of glucose. When glucose levels are low, the …

Since the discovery of myostatin (MSTN; also known as GDF-8) as a critical regulator of
skeletal muscle mass in 1997, there has been an extensive effort directed at understanding …