We report a detailed investigation of the potential of Fe (III) complexes with H4EDTA
derivatives containing different spacers as magnetic resonance imaging (MRI) contrast …

Herein, we present the synthesis and coordination chemistry of copper (II) and zinc (II)
complexes of two novel heterocyclic triazacyclononane (tacn)-based chelators (H NODThia …

Ethylene cross-bridged tetraazamacrocycles are known to produce kinetically stable
transition metal complexes that can act as robust oxidation catalysts under harsh aqueous …

The Cu (II)/Cu (I) conversion involves variation in the coordination number and geometry
around the metal center. Therefore, the flexibility/rigidity of the ligand plays a critical role in …

We present a detailed investigation of the coordination chemistry toward [natCu/64Cu]
copper of a series of H2DEDPA derivatives (H2DEDPA= 6, 6′-((ethane-1, 2-diylbis …

Cyclam-picolinate chelators were functionalized via click chemistry with an additional
carboxyl group for subsequent bioconjugation to antibodies or for the modification of the …

Searching for new compounds and synthetic routes for medical applications is a great
challenge for modern chemistry. Porphyrins, natural macrocycles able to tightly bind metal …

Background Programmed cell death ligand 1 (PD-L1) plays a critical role in the tumor
microenvironment and overexpression in several solid cancers has been reported. This was …

Tetraazamacrocycles, cyclic molecules with four nitrogen atoms, have long been known to
produce highly stable transition metal complexes. Cross-bridging such molecules with two …

Two new ligands were synthesized with the goal of copper stabilization, N, N′-(2-
methylpyridine)-2, 11-diaza [3, 3](2, 6) pyridinophane (PicN4) and N-(methyl), N′-(2 …