Natural killer cells: development, maturation, and clinical utilization

AM Abel, C Yang, MS Thakar… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

Infections and pregnancy: effects on maternal and child health

M Kumar, M Saadaoui, S Al Khodor - Frontiers in Cellular and …, 2022 - frontiersin.org
Pregnancy causes physiological and immunological adaptations that allow the mother and
fetus to communicate with precision in order to promote a healthy pregnancy. At the same …

Commensal microbes provide first line defense against Listeria monocytogenes infection

S Becattini, ER Littmann, RA Carter, SG Kim… - Journal of Experimental …, 2017 - rupress.org
Listeria monocytogenes is a foodborne pathogen that causes septicemia, meningitis and
chorioamnionitis and is associated with high mortality. Immunocompetent humans and …

[HTML][HTML] Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

JT White, EW Cross, MA Burchill, T Danhorn… - Nature …, 2016 - nature.com
Virtual memory cells (VM) are an antigen-specific, memory phenotype CD8 T-cell subset
found in lymphoreplete, unchallenged mice. Previous studies indicated that VM cells were …

CD1d-mediated recognition of an α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution

L Brossay, M Chioda, N Burdin, Y Koezuka… - The Journal of …, 1998 - rupress.org
Natural killer (NK) T cells are a lymphocyte subset with a distinct surface phenotype, an
invariant T cell receptor (TCR), and reactivity to CD1. Here we show that mouse NK T cells …

Evolutionary struggles between NK cells and viruses

LL Lanier - Nature Reviews Immunology, 2008 - nature.com
Natural killer (NK) cells are well recognized for their ability to provide a first line of defence
against viral pathogens and they are increasingly being implicated in immune responses …

Natural killer cells as an initial defense against pathogens

MB Lodoen, LL Lanier - Current opinion in immunology, 2006 - Elsevier
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse
range of pathogens. Recognition of infection by NK cells is accomplished by the activation of …

Memory CD8+ T Cells Provide Innate Immune Protection against Listeria monocytogenes in the Absence of Cognate Antigen

RE Berg, E Crossley, S Murray, J Forman - The Journal of experimental …, 2003 - rupress.org
Interferon (IFN)-γ plays an important role in the innate immune response against intracellular
bacterial pathogens. It is commonly thought that natural killer cells are the primary source of …

TLR‐mediated activation of NK cells and their role in bacterial/viral immune responses in mammals

M Adib‐Conquy, D Scott‐Algara… - Immunology and cell …, 2014 - Wiley Online Library
Natural killer (NK) cells are important in innate immunity, first described as guardians for the
detection and clearance of transformed or virus‐infected cells. Later, this cell type was …

Selective ability of mouse CD1 to present glycolipids: α-galactosylceramide specifically stimulates Vα14+ NK T lymphocytes

N Burdin, L Brossay, Y Koezuka, ST Smiley… - The Journal of …, 1998 - journals.aai.org
Abstract Mouse CD1 (mCD1) glycoproteins are known to present peptides, while human
CD1 molecules present glycolipids. In mice, mCD1-autoreactive NK T cells play critical roles …