Cocrystals are an emerging class of crystalline materials composed of two or more different
molecules in the same crystal lattice that are physically connected by non-ionic and non …

Besides enhancing aqueous solubilities, cocrystals have the ability to fine-tune solubility
advantage over drug, supersaturation index, and bioavailability. This review presents …

How do molecules aggregate in solution, and how do these aggregates consolidate
themselves in crystals? What is the relationship between the structure of a molecule and the …

Recently, drug-drug cocrystal attracts more and more attention. It offers a low risk, low-cost
but high reward route to new and better medicines and could improve the physiochemical …

Abstract Development of novel drug delivery systems (DDS) represents a promising
opportunity to overcome the various bottlenecks associated with the chronic antiretroviral …

Non-covalent derivatives (NCDs) are formed by incorporating one (or more) coformer
molecule (s) into the matrix of a parent molecule via non-covalent forces. These forces can …

Curcumin is a pharmaceutically viable ingredient derived from the rhizome of the Indian
spice turmeric (Curcuma longa). However, curcumin suffers from poor water solubility, which …

In this research work, bicomponent structures of salicylic acid were synthesized by reflux
condition. The cofomers used were 1-10-phenanthroline, 5-chlorobenzotiazole, and 2 …

The focus of the review is to discuss the relevant and essential aspects of pharmaceutical
cocrystals in both academia and industry with an emphasis on non-steroidal anti …

Cocrystals of a weakly basic drug (nevirapine) with acidic coformers are shown to alter the
solubility dependence on pH, and to exhibit a pHmax above which a less soluble cocrystal …