Within a tumor, IL-1β is produced and secreted by various cell types, such as immune cells,
fibroblasts, or cancer cells. The IL1B gene is induced after “priming” of the cells and a …

Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

The association between chronic inflammation and cancer is now well established. This
association has recently received renewed interest with the recognition that microbial …

Helicobacter pylori are spiral-shaped gram-negative bacteria with polar flagella that live
near the surface of the human gastric mucosa. They have evolved intricate mechanisms to …

Tumours contain immune cells and a network of pro-and anti-inflammatory cytokines, which
collaborate in the development and progression of cancer. Cytokine profiles might prove to …

BACKGROUND & AIMS:: Genetic variations in proinflammatory and anti-inflammatory
cytokine genes influence individual response to carcinogenic exposures. Polymorphisms in …

Helicobacter pylori is the main cause of peptic ulceration, distal gastric adenocarcinoma,
and gastric lymphoma. Only 15% of those colonized develop disease, and pathogenesis …

Chronic gastritis induced by Helicobacter pylori is the strongest known risk factor for
adenocarcinoma of the distal stomach, yet only a minority of people who harbour this …

In Asia, the prevalence of Helicobacter pylori (H. pylori) infection varies markedly in different
countries. Higher prevalence rates are found in developing Asian countries while lower …

Chronic inflammatory responses have long been observed to be associated with various
types of cancer and play decisive roles at different stages of cancer development …