Light is the most important Zeitgeber for entraining animal activity rhythms to the 24-h day. In
all animals, the eyes are the main visual organs that are not only responsible for motion and …

The fruit fly Drosophila melanogaster is an established model organism in chronobiology,
because genetic manipulation and breeding in the laboratory are easy. The circadian clock …

The circadian clock and its output pathways play a pivotal role in optimizing daily processes.
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …

Vision enables both image-forming perception, driven by a contrast-based pathway, and
unconscious non-image-forming circadian photoentrainment, driven by an irradiance-based …

The circadian clock orchestrates daily changes in physiology and behavior to ensure
internal temporal order and optimal timing across the day. In animals, a central brain clock …

Drosophila's dorsal clock neurons (DNs) consist of four clusters (DN1as, DN1ps, DN2s, and
DN3s) that largely differ in size. While the DN1as and the DN2s encompass only two …

The circadian clock regulates animal physiological activities. How temperature reorganizes
circadian-dependent physiological activities remains elusive. Here, using in-vivo two-photon …

The master circadian clock generates 24-hour rhythms to orchestrate daily behavior, even
running freely under constant conditions. Traditionally, the master clock is considered self …

Animals react to environmental changes over timescales ranging from seconds to days and
weeks. An important question is how sensory stimuli are parsed into neural signals …

In metazoan organisms, circadian (∼ 24 h) rhythms are regulated by pacemaker neurons
organized in a master–slave hierarchy. Although it is widely accepted that master …