Introduction. Oxidative stress (OS) during inflammation can increase inflammatory
responses and damage tissue. Lipopolysaccharide (LPS) can induce oxidative stress and …

Inflammasomes have become an important natural sensor of host immunity, and can protect
various organs against pathogenic infections, metabolic syndromes, cellular stress and …

Septic acute liver injury is one of the leading causes of fatalities in patients with sepsis. Toll-
like receptor 4 (TLR4) plays a vital role in response to lipopolysaccharide (LPS) challenge …

Background Lipopolysaccharide (LPS) is an endotoxin that leads to inflammation in many
organs, including liver. It binds to pattern recognition receptors, that generally recognise …

Cold is a factor affecting health in humans and animals. The liver, a major metabolic center,
is highly susceptible to ambient air temperature. Recent studies have shown that …

Background Liver has an important role in the initiation and progression of multiple organ
failure that occurs in sepsis. Many natural active substances can be used to reduce the liver …

Systemic or hepatic inflammation is caused by intraperitoneal application of
lipopolysaccharide (LPS). In this study, we investigated anti-inflammatory and antioxidant …

Background: Liver dysfunction impairs immunological homeostasis. Glycine (Gly) has been
reported to have antioxidative and anti-inflammatory effects and to regulate apoptosis in …

Aims and objectives Sepsis-associated liver injury is a common public health problem in
intensive care units. Astragaloside IV (AS-IV) is an active component extracted from the …

This investigation elucidates the impact of sophocarpine treatment on lipopolysaccharide
(LPS) stimulated sepsis-induced cardiomyopathy (SIC) via in vivo and in vitro experiments …