A Singh, JNJ Reynolds - Frontiers in neuroanatomy, 2024 - frontiersin.org
The basal ganglia are involved in motor control and action selection, and their impairment manifests in movement disorders such as Parkinson's disease (PD) and dystonia, among …
Background Polymeric nanoparticles (PNP) have received significant amount of interests for targeted drug delivery across the blood-brain barrier (BBB). Experimental studies have …
SM Mackay, DMA Myint, RA Easingwood… - Communications …, 2019 - nature.com
The unique surface plasmon resonance of hollow gold nanoshells can be used to achieve drug release from liposomes upon laser stimulation, and adapted to mimic the intricate …
W Langhoff, A Riggs, P Hinow - PLoS One, 2018 - journals.plos.org
Drug delivery to the brain is challenging due to the presence of the blood-brain barrier. Mathematical modeling and simulation are essential tools for the deeper understanding of …
Au cours du diabète, l'hyperglycémie provoque des altérations du système vasculaire aggravant les complications cérébrovasculaires comme l'accident vasculaire cérébral. En …
Blood-brain barrier (BBB) is a unique structure in the central nervous system (CNS) that protects the brain from blood borne pathogens. Despites the protection of BBB, millions of …
Cytotoxic anticancer drugs are used to treat cancer, particularly tumors. These drugs themselves do not distinguish between healthy and tumor cells and attack all of them …