▪ Abstract Soft lithography, a set of techniques for microfabrication, is based on printing and
molding using elastomeric stamps with the patterns of interest in bas-relief. As a technique …

The development of DNA-based genetic markers has had a revolutionary impact on animal
genetics. With DNA markers, it is theoretically possible to observe and exploit genetic …

Here we present a draft genome sequence of the common chimpanzee (Pan troglodytes).
Through comparison with the human genome, we have generated a largely complete …

Understanding the relationship between genetic variation and biological function on a
genomic scale is expected to provide fundamental new insights into the biology, evolution …

Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …

Alterations in gene sequences, expression levels and protein structure or function have
been associated with every type of cancer. These'molecular markers' can be useful in …

In two randomly selected human genomes, 99.9% of the DNA sequence is identical. The
remaining 0.1% of DNA contains sequence variations. The most common type of such …

Abstract “If it were not for the great variability among individuals medicine might as well be a
science and not an art.” The thoughts of Sir William Osler in 1892 reflect the view of …

In one of the first major texts in the emerging field of computational molecular biology, Pavel
Pevzner covers a broad range of algorithmic and combinatorial topics and shows how they …

Single nucleotide polymorphisms (SNPs) are valuable genetic markers of human disease 1,
2, 3. They also comprise the highest potential density marker set available for mapping …