Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …

Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …

The antimalarial drug artemisinin and its derivatives have been explored as potential
anticancer agents, but their underlying mechanisms are controversial. In this study, we found …

Currently, there is no effective treatment for Burkitt's lymphoma in patients aged above 60
years, and thus research on effective treatment options for Burkitt's lymphoma has been …

Artemisinin-based therapies are the only effective treatment for malaria, the most
devastating disease in human history. To meet the growing demand for artemisinin and …

In addition to the role of programmed cell death ligand 1 (PD-L1) in facilitating tumour cells
escape from immune surveillance, it is considered as a crucial effector in transducing …

Introduction: Terpenoids constitute the largest class of natural products and are a rich
reservoir of candidate compounds for drug discovery. Recent efforts into the research and …

Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …

Improvement of quality of life and survival of cancer patients will be greatly enhanced by the
development of highly effective drugs to selectively kill malignant cells. Artemisinin and its …

Redox dysregulation originating from metabolic alterations and dependence on mitogenic
and survival signaling through reactive oxygen species represents a specific vulnerability of …