Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …

It has been one and a half centuries since Enrico Sertoli published the seminal discovery of
the testicular 'nurse cell', not only a key cell in the testis, but indeed one of the most amazing …

Abstract Background Microplastics (MPs), which are smaller in size and difficult to degrade,
can be easily ingested by marine life and enter mammals through the food chain. Our …

STUDY QUESTION How is the semen quality of sexually active men following recovery from
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection? SUMMARY …

Male infertility is an attracting growing concern owing to decline in sperm quality of men
worldwide. Phthalates, in particular to di (2-ethylhexyl) phthalate (DEHP) or its main …

Spermatogenesis requires intricate interactions between the germline and somatic cells.
Within a given cross section of a seminiferous tubule, multiple germ and somatic cell types …

Background Varicocele (VC) is present in 35-40% of men with infertility. However, current
surgical and antioxidant treatments are not completely effective. In addition to oxidative …

Evaluation of testicular functions (production of sperm and androgens) is an important
aspect of preclinical safety assessment and testicular toxicity is comparatively far more …

The testis produces sperm throughout the male reproductive lifespan by balancing self-
renewal and differentiation of spermatogonial stem cells (SSCs). Part of the SSC niche is …

Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited
sequelae depending on the pathogen. Here, we consider the role of infection during …