Peptide hormones play a prominent role in controlling energy homeostasis and metabolism.
They have been implicated in controlling appetite, the function of the gastrointestinal and …

Neuropeptide W (NPW) and neuropeptide B (NPB) are two structurally and functionally
related regulatory peptides, which are highly expressed in several brain regions and …

Metabolic activities of orexin A (OXA) in mature adipocytes are mediated via PI3K/PKB and
PPARγ. However, the effects of OXA on preadipocytes are largely unknown. We report here …

The 2 structurally and functionally related peptides, neuropeptide B (NPB) and neuropeptide
W (NPW), together with their receptor (s)(NPBWR1/NPBWR2) constitute the NPB/NPW …

Obestatin is a 23-amino acid peptide encoded by the ghrelin gene, which regulates food
intake, body weight and insulin sensitivity. Obestatin influences glucose and lipid …

Objective: Neuropeptide W (NPW), an endogenous ligand for the G protein-coupled receptor
7 (GPR7), was first found to make important roles in central nerve system. In periphery, NPW …

Neuropeptide W (NPW), which was first isolated from the porcine hypothalamus, exists in
two forms, consisting of 23 (NPW23) or 30 (NPW30) amino acids. These neuropeptides bind …

Neuropeptide B (NPB) regulates food intake, energy homeostasis and hormone secretion in
mammals via two G-protein coupled receptors, termed as GPR 7 and GPR 8. However, there …

Abstract Neuropeptides B and W (NPB and NPW) are endogenous ligands of the
Neuropeptide B/W Receptor 1 (NPBWR1) which has been implicated in a wide range of …

The use of morphine is controversial due to the incidence of rewarding behavior, respiratory
depression, and tolerance, leading to increased drug dose requirements, advancing to …