Gliclazide: biopharmaceutics characteristics to discuss the biowaiver of immediate and extended release tablets

BC Mapa, LU Araújo, NM Silva-Barcellos… - Applied Sciences, 2020 - mdpi.com
Featured Application In line with the principles of the Pan American Health Organization and
the World Health Organization (WHO), which permeates the development of technical …

Insights into the impact of cross-linking processes on physicochemical characteristics and mucoadhesive potential of gellan gum/retrograded starch microparticles as …

VM de Oliveira Cardoso, RC Evangelista… - Journal of Drug Delivery …, 2020 - Elsevier
Polymer microparticles have been regarded a promising system for drug delivery. In this
paper, ionic cross-linking (IC) and dual cross-linking (DC)(ionic/covalent) processes were …

Thermal analysis study of solid dispersions hydrochlorothiazide

CMP de Souza, JAB dos Santos… - Journal of Thermal …, 2018 - Springer
Solid dispersions (SD) are used as a technological strategy to increase the aqueous
dissolution rate of poorly soluble active pharmaceutical ingredients, such as …

[HTML][HTML] Prednisone raw material characterization and formulation development

LH Toehwé, LD Prado, HVA Rocha - Brazilian Journal of …, 2018 - SciELO Brasil
Solid dosage forms for oral use, particularly tablets, are the most highly used dosage forms
in therapy because they are easily administered, have high productivity and relatively low …

[HTML][HTML] Development, characterization and evaluation of the dissolution profile of sulfasalazine suspensions

MAB Costa, ALV Villa, RCSA Barros… - Brazilian Journal of …, 2015 - SciELO Brasil
This paper reports the development, characterization and in vitrodissolution behavior of
sulfasalazine suspensions for treatment of chronic intestinal inflammatory diseases. Three …

Assay and physicochemical characterization of the antiparasitic albendazole

NCT Cavalcanti, GD Sousa, MAM Tabosa… - Brazilian Journal of …, 2012 - SciELO Brasil
The aim of this study was to characterize three batches of albendazole by pharmacopeial
and complementary analytical techniques in order to establish more detailed specifications …

Thermal behavior and compatibility analysis of the new chemical entity LPSF/FZ4

SPM Costa, KER da Silva, GCR de Medeiros… - Thermochimica …, 2013 - Elsevier
In this study, differential scanning calorimetry and thermogravimetry were employed to
determine the thermal behavior of LPSF/FZ4 isolated and associated with excipients (amide …

Polymorphic stability of darunavir and its formulation

JCR Corrêa, AG Perissinato, CH dos Reis Serra… - Journal of Thermal …, 2016 - Springer
Darunavir (DAR) is a synthetic antiretroviral drug widely used around the world as an
important component of HIV therapy. Usually, DAR is commercialized at ethanolate …

Determination of the main solid-state form of albendazole in bulk drug, employing Raman spectroscopy coupled to multivariate analysis

NL Calvo, JM Arias, AB Altabef, RM Maggio… - … of Pharmaceutical and …, 2016 - Elsevier
Albendazole (ALB) is a broad-spectrum anthelmintic, which exhibits two solid-state forms
(Forms I and II). The Form I is the metastable crystal at room temperature, while Form II is the …

Fipronil tablets: development and pharmacokinetic profile in beagle dogs

GCM Dos Santos, LHG Rosado, MCC Alves… - Aaps Pharmscitech, 2020 - Springer
Increased human–pet interactions have led to concerns related to the prevention and
treatment of ectoparasite infestations. Fipronil (FIP) is a widely used ectoparasiticide in …