Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Approximately a century ago, in 1916, the term 'hydrotropy'was coined by the scientist Carl
A. Neuberg to address anionic organic salts which considerably augmented the aqueous …

The clouding development and the association of the mixture of surfactant and antidiabetic
drug metformin hydrochloride (MNH) have been investigated in aq. solutions of two anionic …

Drug molecules' therapeutic efficacy depends on their bioavailability and solubility. But more
than 70% of the formulated drug molecules show limited effectiveness due to low water …

Hydrotropes, such as sodium alkyl benzene sulfonates and sodium butyl monoglycol sulfate,
were used for the selective extraction of piperine by cell permeabilization of Piper nigrum …

The signature of hydrotropic solubilisation is the sigmoidal solubility curve; when plotted
against hydrotrope concentration, solubility increases suddenly after the minimum …

Solubilization of poorly water-soluble drugs has been a very important issue in screening
studies of new chemical entities as well as formulation research. Various techniques are …

A novel hydrotropy-based extraction method for selective extraction of curcuminoids from
Curcuma longa (turmeric) was investigated. The degree of extraction was dependent upon …

The hydrotropes are a special class of compounds that exhibit distinct solution properties.
They may self-associate in aqueous medium, comparable to amphiphile self-association or …

In this paper, we show how to tailor the structure and rheology of aqueous solutions of the
cationic surfactant cetyltrimethylammonium tosylate, CTAT, by adding a hydrotrope …