Combined-electrical optogenetic stimulation but not channelrhodopsin kinetics improves the fidelity of high rate stimulation in the auditory pathway in mice

EA Ajay, AC Thompson, AA Azees, AK Wise… - Scientific Reports, 2024 - nature.com
Novel stimulation methods are needed to overcome the limitations of contemporary cochlear
implants. Optogenetics is a technique that confers light sensitivity to neurons via the genetic …

Fraxicon for optical applications with aperture∼ 1 mm: characterisation study

H Mu, D Smith, SH Ng, V Anand, NHA Le… - Nanomaterials, 2024 - mdpi.com
Emerging applications of optical technologies are driving the development of miniaturised
light sources, which in turn require the fabrication of matching micro-optical elements with …

Fraxicon for Optical Applications with Aperture∼ 1 mm

H Mu, D Smith, SH Ng, V Anand, NHA Le… - 2023 - preprints.org
Emerging applications of optical technologies are driving the development of miniaturised
light sources, which in turn require the fabrication of matching micro-optical elements with …

Hybrid Optogenetic and Electrical Stimulation of Retinal Ganglion Cells for Artificial Vision

W Tong, W Kwan, E Brunton, J Begeng, T Kameneva… - 2024 - researchsquare.com
Millions of adults worldwide experience severe visual impairment due to photoreceptor loss
from retinal diseases such as retinitis pigmentosa and macular degeneration. Retinal …

Impact of opsin kinetics on high-rate stimulation of the auditory nerve in mice

EA Ajay, AC Thompson, AA Azees, A Wise… - 2024 - researchsquare.com
Optogenetic stimulation improves spectral resolution compared to electrical stimulation in
preclinical cochlear implant studies but remains unreliable at the high stimulation rates …