Perspectives on liquid biopsy for label‐free detection of “circulating tumor cells” through intelligent lab‐on‐chips

L Miccio, F Cimmino, I Kurelac, MM Villone, V Bianco… - View, 2020 - Wiley Online Library
Circulating tumor cells (CTCs) are rare tumor cells released from primary, metastatic, or
recurrent tumors in the peripheral blood of cancer patients. CTCs isolation from peripheral …

[HTML][HTML] Current approaches for avoiding the limitations of circulating tumor cells detection methods—implications for diagnosis and treatment of patients with solid …

A Kowalik, M Kowalewska, S Góźdź - Translational Research, 2017 - Elsevier
Eight million people die of cancer each year and 90% of deaths are caused by systemic
disease. Circulating tumor cells (CTCs) contribute to the formation of metastases and thus …

In vivo liquid biopsy using Cytophone platform for photoacoustic detection of circulating tumor cells in patients with melanoma

EI Galanzha, YA Menyaev, AC Yadem… - Science translational …, 2019 - science.org
Most cancer deaths arise from metastases as a result of circulating tumor cells (CTCs)
spreading from the primary tumor to vital organs. Despite progress in cancer prognosis, the …

Characterising the phenotypic evolution of circulating tumour cells during treatment

SCH Tsao, J Wang, Y Wang, A Behren, J Cebon… - Nature …, 2018 - nature.com
Real-time monitoring of cancer cells' phenotypic evolution during therapy can provide vital
tumour biology information for treatment management. Circulating tumour cell (CTC) …

[HTML][HTML] Liquid biopsy utility for the surveillance of cutaneous malignant melanoma patients

SK Huang, DSB Hoon - Molecular oncology, 2016 - Elsevier
Cutaneous melanoma is one of the highest incident-rate cancers with increasing prevalence
in Western societies. Despite the advent of new approved therapeutics, the 5-year overall …

Twenty years on: what do we really know about Ewing sarcoma and what is the path forward?

E Lawlor, PH Sorensen - Critical Reviews™ in Oncogenesis, 2015 - dl.begellhouse.com
Ewing sarcoma (ES) is a highly aggressive bone and soft-tissue tumor with peak incidence
among adolescents and young adults. Despite advances in local control and systemic …

[HTML][HTML] Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma

M Lodrini, A Sprüssel, K Astrahantseff, D Tiburtius… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The invasive nature of surgical biopsies deters sequential application, and single biopsies
often fail to reflect tumor dynamics, intratumor heterogeneity and drug sensitivities likely to …

Liquid biopsy in melanoma: significance in diagnostics, prediction and treatment monitoring

P Kamińska, K Buszka, M Zabel, M Nowicki… - International Journal of …, 2021 - mdpi.com
Liquid biopsy is a common term referring to circulating tumor cells and other biomarkers,
such as circulating tumor DNA (ctDNA) or extracellular vesicles. Liquid biopsy presents a …

Current trends in circulating biomarkers for melanoma detection

N Huang, KJ Lee, MS Stark - Frontiers in Medicine, 2022 - frontiersin.org
Melanomas have increased in global incidence and are the leading cause of skin cancer
deaths. Whilst the majority of early-stage, non-metastatic melanomas can be cured with …

A multiparameter liquid biopsy approach allows to track melanoma dynamics and identify early treatment resistance

MC Scaini, C Catoni, C Poggiana, J Pigozzo… - NPJ Precision …, 2024 - nature.com
Melanoma heterogeneity is a hurdle in metastatic disease management. Although the
advent of targeted therapy has significantly improved patient outcomes, the occurrence of …