▪ Abstract Stomatal guard cells are unique as a plant cell model and, because of the depth of
present knowledge on ion transport and its regulation, offer a first look at signal integration in …

The epithelial Na+ channel (ENaC) is a pathway for Na+ transport across epithelia,
including the kidney collecting duct, lung, and distal colon. ENaC is critical for Na+ …

Neutrophil elastase is a serine protease that is abundant in the airways of individuals with
cystic fibrosis (CF), a genetic disease manifested by excessive airway Na+ absorption and …

Abstract Analysis of the Arabidopsis thaliana endomembrane system has shown that plant
cell viability depends on a properly functioning vacuole and intact vesicular trafficking. The …

The epithelial Na+ channel (ENaC) is a major regulator of salt and water reabsorption in a
number of epithelial tissues. Abnormalities in ENaC function have been directly linked to …

Abstract The epithelial Na+ channel (ENaC) forms the pathway for Na+ absorption in the
kidney collecting duct and other epithelia. Dominant gain-of-function mutations cause …

The focus of this review is on the principal sensory ending of the mammalian muscle
spindle, known as the primary ending. The process of mechanosensory transduction in the …

Cystic fibrosis (CF) is one of the most common lethal genetic disorders. It results primarily
from mutations in the cystic fibrosis transmembrane conductance regulator (cftr) gene. These …

The aldosterone-sensitive distal nephron (ASDN) includes the late distal convoluted tubule
2, the connecting tubule (CNT) and the collecting duct. The appropriate regulation of sodium …

High grade glioma cells derived from patient biopsies express an amiloride-sensitive
sodium conductance that has properties attributed to the human brain sodium channel …