Mycobacterium tuberculosis cough aerosol culture status associates with host characteristics and inflammatory profiles

V Nduba, LN Njagi, W Murithi, Z Mwongera… - Nature …, 2024 - nature.com
Interrupting transmission events is critical to tuberculosis control. Cough-generated aerosol
cultures predict tuberculosis transmission better than microbiological or clinical markers. We …

Tuberculosis: An Update for the Clinician

S Janssen, M Murphy, C Upton, B Allwood… - …, 2025 - Wiley Online Library
Tuberculosis (TB) remains a significant global health threat with high mortality and efforts to
meet WHO End TB Strategy milestones are off‐track. It has become clear that TB is not a …

The Titanic question in TB control: Should we worry about the bummock?

SM Fortune - Proceedings of the National Academy of …, 2024 - National Acad Sciences
In the study of sea ice, the portion of an iceberg that sits below the water is known as the
bummock, counterpart to the hummock, the visible crest of ice. As amateur oceanographers …

Mycobacterium tuberculosis transmission: the importance of precision

R Dinkele, PY Khan, DF Warner - The Lancet Infectious Diseases, 2024 - thelancet.com
The identification of Mycobacterium tuberculosis as a causal agent of tuberculosis
revolutionised the understanding of human diseases by showing that some have an …

A spotlight on the tuberculosis epidemic in South Africa

M IZRAH - nature communications, 2024 - nature.com
Tuberculosis is the leading cause of death from a single infectious agent, with over 25% of
these occurring in the African region. Multi-drug resistant strains which do not respond to first …

[PDF][PDF] What Mice Can Teach Us about How to Stop Drug-Resistant Tuberculosis: Correct Chemotherapy Regimen and Patient Compliance are the Key

I Mokrousov, T Vinogradova, M Dogonadze… - Biomedical and …, 2024 - besjournal.com
Despite well-known limitations, mice remain useful as model animals to study tuberculosis
(TB) pathogenesis, the basic immune response, the extent of lung pathology as well as …

[HTML][HTML] Persistent Mycobacterium tuberculosis bioaerosol release in a tuberculosis-endemic setting

R Dinkele, S Gessner, B Patterson, A McKerry… - medRxiv, 2024 - ncbi.nlm.nih.gov
Pioneering studies linking symptomatic disease and cough-mediated release of
Mycobacterium tuberculosis (Mtb) established the infectious origin of tuberculosis (TB) …

Tuberculosis transmission in South Africa: A need for a new paradigm?

R Wood, LG Bekker - South African Medical Journal, 2024 - journals.co.za
Tuberculosis (TB) control is failing in South Africa (SA), with current notification rates as high
as those reported in the early 1900s.[1, 2] Adjusting for population size, SA remains ranked …

Candidate transmission survival genome of Mycobacterium tuberculosis

S Mishra, PR Singh, X Hu, L Lopez-Quezada, A Jinich… - bioRxiv, 2025 - biorxiv.org
Mycobacterium tuberculosis (Mtb), a leading cause of death from infection, completes its life
cycle entirely in humans except for transmission through the air. To begin to understand how …

[PDF][PDF] Reply to "Mirage de tuberculose in the 21st century".

B Patterson, R Wood - Public Health Action, 2024 - pdfs.semanticscholar.org
We believe the mirage de tuberculose phenomenon may be more common than generally
realised. Our findings, published recently in the Proceedings of National Academies of …