Formins in human disease

L Labat-de-Hoz, MA Alonso - Cells, 2021 - mdpi.com
Almost 25 years have passed since a mutation of a formin gene, DIAPH1, was identified as
being responsible for a human inherited disorder: a form of sensorineural hearing loss …

Intrauterine Growth Restriction: Need to Improve Diagnostic Accuracy and Evidence for a Key Role of Oxidative Stress in Neonatal and Long-Term Sequelae

E Nüsken, S Appel, L Saschin, C Kuiper-Makris… - Cells, 2024 - mdpi.com
Intrauterine growth restriction (IUGR) and being small for gestational age (SGA) are two
distinct conditions with different implications for short-and long-term child development. SGA …

Adaptive structural and functional evolution of the placenta protects fetal growth in high-elevation deer mice

K Wilsterman, EC Moore… - Proceedings of the …, 2023 - National Acad Sciences
Environmental hypoxia challenges female reproductive physiology in placental mammals,
increasing rates of gestational complications. Adaptation to high elevation has limited many …

FGR-associated placental insufficiency and capillary angiogenesis involves disruptions in human placental miRNAs and mRNAs

W Song, Q Guo, M Puttabyatappa, VR Elangovan… - Heliyon, 2024 - cell.com
Fetal growth restriction (FGR) is one of the most common pregnancy complications
culminating in adverse fetal outcome, including preterm birth, neonatal mortality and …

Potential Association of Gut Microbial Metabolism and Circulating mRNA Based on Multiomics Sequencing Analysis in Fetal Growth Restriction

H Tang, D Li, J Peng, W Yang… - Mediators of …, 2024 - Wiley Online Library
Objective. Fetal growth restriction (FGR) is a significant contributor to negative pregnancy
and postnatal developmental outcomes. Currently, the exact pathological mechanism of …

Effects of N-Acetylcysteine on the proliferation, hormone secretion level, and gene expression profiles of goat ovarian granulosa cells

T Ji, X Chen, Y Zhang, K Fu, Y Zou, W Wang, J Zhao - Genes, 2022 - mdpi.com
The purpose of this paper was to investigate the effects of N-acetylcysteine (NAC) on the
proliferation, hormone secretion, and mRNA expression profiles of ovarian granulosa cells …

Dishevelled-Associated Activator of Morphogenesis 2 (DAAM2) predicts the immuno-hot phenotype in pancreatic adenocarcinoma

Q Zhang, J Pan, H Nie, H Wang, F An… - Frontiers in Molecular …, 2022 - frontiersin.org
Background: DAAM2 participates in the oncogenesis and progression of human cancers.
Although the role of DAAM2 in cancers has been preliminarily investigated, its correlations …

Placental DAAM2 is unaltered in preeclampsia, but upregulated by treatment with proton pump inhibitors

N De Alwis, S Beard, NK Binder, N Pritchard… - Pregnancy …, 2022 - Elsevier
Abstract Background Dishevelled Associated Activator Of Morphogenesis 2 (DAAM2) levels
are elevated in the maternal circulation and placenta in pregnancies complicated by fetal …

Intrauterine Growth Restriction: Improving Diagnostic Accuracy and the Role of Oxidative Stress in Neonatal and Long-Term Sequels

E Nüsken, S Appel, L Saschin, C Kuiper-Makris… - 2023 - preprints.org
Intrauterine growth restriction (IUGR) and being born small for gestational age (SGA) are two
distinct conditions with different implications for child development. IUGR is associated with …

Клiтинна вiдповiдь на гiпоксiю у ворсинчастому хорiонi плацент вiд жiнок пiзнього репродуктивного вiку з вагiтнiстю, iндукованою в програмах IVF

ОМ Носенко, ФО Ханча - 2023 - repo.odmu.edu.ua
Ризик несприятливих результатiв, пов'язаних iз субоптимальною плацентацiєю, у
вагiтних пiсля допомiжних репродуктивних технологiй (ДРТ) значно вищий, нiж у …