The renoprotective effect of esaxerenone independent of blood pressure lowering: a post hoc mediation analysis of the ESAX-DN trial

Y Okuda, S Ito, N Kashihara, K Shikata… - Hypertension …, 2023 - nature.com
Angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs)
are recommended as first-line drugs for hypertension with diabetic nephropathy owing to …

Complete effect decomposition for an arbitrary number of multiple ordered mediators with time-varying confounders: A method for generalized causal multi-mediation …

AS Tai, SH Lin - Statistical Methods in Medical Research, 2023 - journals.sagepub.com
Causal mediation analysis is advantageous for mechanism investigation. In settings with
multiple causally ordered mediators, path-specific effects have been introduced to specify …

Causal mediation analysis with multiple time-varying mediators

AS Tai, SH Lin, YC Chu, T Yu, MA Puhan… - …, 2023 - journals.lww.com
In longitudinal studies with time-varying exposures and mediators, the mediational g-formula
is an important method for the assessment of direct and indirect effects. However, current …

The effect of acupuncture on exercise capacity in patients with COPD is mediated by improvements of dyspnea and leg fatigue: a causal mediation analysis using data …

T Kayo, M Suzuki, T Mitsuma, F Fukuda - BMC Complementary Medicine …, 2024 - Springer
Background Acupuncture is known to improve exercise capacity in patients with chronic
obstructive pulmonary disease (COPD), but its mechanism remains unknown. Whether …