Imidazoles as potential anticancer agents: An update on recent studies

P Sharma, C LaRosa, J Antwi, R Govindarajan… - Molecules, 2021 - mdpi.com
Nitrogen-containing heterocyclic rings are common structural components of marketed
drugs. Among these heterocycles, imidazole/fused imidazole rings are present in a wide …

Pyridine scaffolds, phenols and derivatives of azo moiety: current therapeutic perspectives

T Tahir, M Ashfaq, M Saleem, M Rafiq, MI Shahzad… - Molecules, 2021 - mdpi.com
Synthetic heterocyclic compounds have incredible potential against different diseases;
pyridines, phenolic compounds and the derivatives of azo moiety have shown excellent …

IP‐Se‐06, a Selenylated Imidazo[1,2‐a]pyridine, Modulates Intracellular Redox State and Causes Akt/mTOR/HIF‐1α and MAPK Signaling Inhibition, Promoting …

DC Dos Santos, J Rafique, S Saba… - Oxidative Medicine …, 2022 - Wiley Online Library
Glioblastoma multiforme (GBM) is a notably lethal brain tumor associated with high
proliferation rate and therapeutic resistance, while currently effective treatment options are …

Synthesis of new set of imidazo [1, 2-a] pyridine-schiff bases derivatives as potential antimicrobial agents: Experimental and theoretical approaches

O Roby, FZ Kadiri, Z Loukhmi, M Moutaouakil… - Journal of Molecular …, 2023 - Elsevier
Multidrug resistance in microbial infections necessitates the discovery of new drugs with
enhanced efficacy. In this context, a novel series of imidazopyridine Schiff bases derivatives …

Novel piperazine based compounds as potential inhibitors for SARS-CoV-2 Protease Enzyme: Synthesis and molecular docking study

AZ Omar, TM Mosa, SK El-Sadany, EA Hamed… - Journal of Molecular …, 2021 - Elsevier
Structurally diverse piperazine-based compounds hybrid with thiadiazole, isatin or with
sulfur/nitrogen, functionalities were synthesized. The structures of the new compounds were …

1,3,4-Oxadiazole N-Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities

LH Al-Wahaibi, AAB Mohamed, SS Tawfik, HM Hassan… - Molecules, 2021 - mdpi.com
The reaction of 5-(3, 4-dimethoxyphenyl)-1, 3, 4-oxadiazole-2 (3 H)-thione 3 with
formaldehyde solution and primary aromatic amines or 1-substituted piperazines, in ethanol …

Synthesis of 4-alkylaminoimidazo[1,2-a]pyridines linked to carbamate moiety as potent α-glucosidase inhibitors

M Saeedi, M Raeisi-Nafchi, S Sobhani, SS Mirfazli… - Molecular Diversity, 2021 - Springer
In this work, various imidazo [1, 2-a] pyridines linked to carbamate moiety were designed,
synthesized, and evaluated for their α-glucosidase inhibitory activity. Among synthesized …

Synthesis, study of antileishmanial and antitrypanosomal activity of imidazo pyridine fused triazole analogues

A Nandikolla, S Srinivasarao, BK Kumar… - RSC …, 2020 - pubs.rsc.org
Four groups, thirty-five compounds in total, of novel 1, 2, 3-triazole analogues of imidazo-[1,
2-a]-pyridine-3-carboxamides were designed and synthesized using substituted pyridine …

Synthesis and anticancer evaluation of amide derivatives of imidazo-pyridines

CS Rani, AG Reddy, E Susithra, KK Mak… - Medicinal Chemistry …, 2021 - Springer
A novel series of amide functionalized imidazo [1, 2-a] pyridine (14a–14j) derivatives were
synthesized and screened for their anticancer activities against breast (MCF-7 and MDA-MB …

Synthesis and Antibacterial Activity of New Imidazo[1,2-a]pyridines Festooned with Pyridine, Thiazole or Pyrazole Moiety

I Althagafi, E Abdel-Latif - Polycyclic Aromatic Compounds, 2022 - Taylor & Francis
Abstract A series of new 6, 8-dichloro-imidazo [1, 2-a] pyridine derivatives incorporating
pyridine, thiazole, and pyrazole ring systems was synthesized. The synthetic strategy of …