1. Introduction Since its introduction in clinical practice in the early 1990's negative pressure
wounds therapy (NPWT) has become widely used in the management of complex wounds in …

Because China is becoming an aging society, the incidence of diabetes and diabetic foot
have been increasing. Diabetic foot has become one of the main health-related killers due to …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

Antibiotic‐loaded bone cement (ALBC) is broadly used to treat orthopaedic infections based
on the rationale that high‐dose local delivery is essential to eradicate biofilm‐associated …

Negative pressure wound therapy with instillation (NPWTi) and dwell time is an adjunctive
treatment modality for selected complex wounds. Because of the greater amount of research …

Background Infection is a common epiphenomenon of advanced diabetic foot disease and
the most common reason for diabetes-related hospitalizations and lower extremity …

Abstract Multicenter, phase‐4, randomized, comparative‐efficacy study in patients with VLUs
or DFUs comparing for noninferiority the percentage change in target ulcer dimensions …

Wound healing is a long-term, multi-stage biological process that mainly includes
haemostatic, inflammatory, proliferative and tissue remodelling phases. Controlling infection …

Negative pressure wound therapy with instillation (NPWTi) has the dual function of negative
pressure sealing drainage and irrigation, which overcomes the disadvantages of NPWT …

Recent scientific evidence on DFI strongly supports the value of multidisciplinary and some
new care models, guideline-based management, more preventive approaches, and …