PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

Mechanisms of drug release in nanotherapeutic delivery systems

PT Wong, SK Choi - Chemical reviews, 2015 - ACS Publications
Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …

Pulsed-field gradient nuclear magnetic resonance measurements (PFG NMR) for diffusion ordered spectroscopy (DOSY) mapping

G Pagès, V Gilard, R Martino, M Malet-Martino - Analyst, 2017 - pubs.rsc.org
While NMR is the most used analytical method for determining the molecular structure of
isolated chemical entities, small compounds as well as macromolecules, its capability of …

Multifunctional lactobionic acid-modified dendrimers for targeted drug delivery to liver cancer cells: investigating the role played by PEG spacer

F Fu, Y Wu, J Zhu, S Wen, M Shen… - ACS applied materials & …, 2014 - ACS Publications
We report the development of a lactobionic acid (LA)-modified multifunctional dendrimer-
based carrier system for targeted therapy of liver cancer cells overexpressing …

An RGD-modified hollow silica@ Au core/shell nanoplatform for tumor combination therapy

X Li, L Xing, Y Hu, Z Xiong, R Wang, X Xu, L Du… - Acta Biomaterialia, 2017 - Elsevier
The combination of chemotherapy and photothermal therapy (PTT) in multifunctional
nanoplatforms to improve cancer therapeutic efficacy is of great significance while it still …

Nanomaterials engineering for drug delivery: a hybridization approach

MR Mohammadi, A Nojoomi, M Mozafari… - Journal of Materials …, 2017 - pubs.rsc.org
The last twenty years have witnessed great advances in biology, medicine, and materials
science, leading to the development of various nanoparticle (NP)-mediated drug delivery …

Peganum harmala Alkaloids and Tannic Acid Encapsulated in PAMAM Dendrimers: Improved Anticancer Activities as Compared to Doxorubicin

HMES Azzazy, AM Sawy, A Abdelnaser… - ACS Applied Polymer …, 2022 - ACS Publications
pH-responsive dual-loaded nanoplatforms based on polyamidoamine dendrimer with a
hydroxyl-terminated surface (PAMAM–OH), generations 3, 4, and 5 (G3, G4, and G5 …

RGD peptide-modified multifunctional dendrimer platform for drug encapsulation and targeted inhibition of cancer cells

X He, CS Alves, N Oliveira, J Rodrigues, J Zhu… - Colloids and Surfaces B …, 2015 - Elsevier
Abstract Development of multifunctional nanoscale drug-delivery systems for targeted
cancer therapy still remains a great challenge. Here, we report the synthesis of cyclic …

Dendritic polyurethane-based prodrug as unimolecular micelles for precise ultrasound-activated localized drug delivery

W Chen, P Liu - Materials Today Chemistry, 2022 - Elsevier
Ultrasound has been recognized as an exciting tool to enhance the therapeutic efficacy in
tumor chemotherapy owing to the triggered drug release, facilitated intracellular drug …

Radiation‐sensitive dendrimer‐based drug delivery system

SY Wu, HY Chou, CH Yuh, SL Mekuria… - Advanced …, 2018 - Wiley Online Library
Combination of chemotherapy and radiotherapy is used to enhance local drug delivery
while reducing off‐target tissue effects. Anticancer drug doxorubicin (DOX) is loaded into l …