Cardiac troponins: contemporary biological data and new methods of determination

A Chaulin - Vascular health and risk management, 2021 - Taylor & Francis
Laboratory diagnosis plays one of the key roles in the diagnosis of many diseases, including
cardiovascular diseases (CVD). The methods underlying the in vitro study of many CVD …

Progress, opportunities, and challenges of troponin analysis in the early diagnosis of cardiovascular diseases

X Du, X Su, W Zhang, S Yi, G Zhang, S Jiang… - Analytical …, 2021 - ACS Publications
Cardiovascular diseases (CVD) have one of the leading mortalities throughout the world; an
estimated 17.9 million people died from CVD in 2019, representing 32% of all global deaths …

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the …

JP Collet, H Thiele, E Barbato… - European heart …, 2021 - academic.oup.com
comprehensive review of the published evidence for management of a given condition
according to ESC Committee for Practice Guidelines (CPG) policy. A critical evaluation of …

Skeletal muscle disorders: a noncardiac source of cardiac troponin T

J du Fay de Lavallaz, A Prepoudis, MJ Wendebourg… - Circulation, 2022 - Am Heart Assoc
Background: Cardiac troponin (cTn) T and cTnI are considered cardiac specific and
equivalent in the diagnosis of acute myocardial infarction. Previous studies suggested rare …

Single high-sensitivity point-of-care whole-blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk

FS Apple, SW Smith, JH Greenslade, Y Sandoval… - Circulation, 2022 - Am Heart Assoc
Background: High-sensitivity cardiac troponin (hs-cTn) laboratory assays are used to rule
out myocardial infarction (MI) on presentation, but prolonged result turnaround times can …

Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities

L Cullen, PO Collinson, E Giannitsis - Emergency Medicine Journal, 2022 - emj.bmj.com
Methods to improve the safety, accuracy and efficiency of assessment of patients with
suspected acute coronary symptoms have occupied decades of study and have supported …

Variability of cardiac troponin levels in normal subjects and in patients with cardiovascular diseases: analytical considerations and clinical relevance: A consensus …

A Clerico, M Zaninotto, A Aimo… - Clinical Chemistry and …, 2023 - degruyter.com
In accordance with all the most recent international guidelines, the variation of circulating
levels of cardiac troponins I and T, measured with high-sensitivity methods (hs-cTnI and hs …

Single Troponin Measurement to Rule Out Myocardial Infarction: JACC Review Topic of the Week

AS Jaffe, R Body, NL Mills, KM Aakre… - Journal of the American …, 2023 - jacc.org
The term “single-sample rule-out” refers to the ability of very low concentrations of high-
sensitivity cardiac troponin (hs-cTn) on presentation to exclude acute myocardial infarction …

High-sensitivity cardiac troponins in pediatric population

A Clerico, A Aimo, M Cantinotti - Clinical Chemistry and Laboratory …, 2022 - degruyter.com
Apparently healthy children often complain of chest pain, especially after physical exercise.
Cardiac biomarker levels are often measured, but the clinical relevance of these assays in …

Novel criteria for the observe-zone of the ESC 0/1h-hs-cTnT algorithm

P Lopez-Ayala, T Nestelberger, J Boeddinghaus… - Circulation, 2021 - Am Heart Assoc
Background: The non–ST-segment–elevation myocardial infarction (NSTEMI) guidelines of
the European Society of Cardiology (ESC) recommend a 3h cardiac troponin determination …