The human tissue kallikrein gene family was, until recently, thought to consist of only three
genes. Two of these human kallikreins, prostate-specific antigen and human glandular …

Human tissue kallikreins (hKs), which are encoded by the largest contiguous cluster of
protease genes in the human genome, are secreted serine proteases with diverse …

We report the development of a previously undescribed gold nanoparticle bio-barcode
assay probe for the detection of prostate specific antigen (PSA) at 330 fg/mL, automation of …

Tissue kallikreins are members of the S1 family (clan SA) of trypsin-like serine proteases
and are present in at least six mammalian orders. In humans, tissue kallikreins (hK) are …

Recent studies on human kallikrein 2 (hK2) have revealed striking similarities and significant
differences with the closely related kallikrein PSA. Both PSA and hK2 are primarily localized …

Prostate-specific antigen (PSA) is a valuable tumor marker for the diagnosis and
management of prostate cancer. The name was intended to underscore the tissue specificity …

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective
biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family …

Prostate-specific antigen (PSA) is a serine protease secreted by both normal prostate
glandular cells and prostate cancer cells. The major proteolytic substrates for PSA are the …

Human tissue kallikreins (KLKs) are attracting increased attention due to their role as
biomarkers for the screening, diagnosis, prognosis, and monitoring of various cancers …

The human tissue kallikrein and kallikrein-related peptidases (KLKs), encoded by the largest
contiguous cluster of protease genes in the human genome, are secreted serine proteases …