A Photosensitized Singlet Oxygen (1O2) Toolbox for Bio-Organic Applications: Tailoring 1O2 Generation for DNA and Protein Labelling, Targeting and Biosensing

D Aerssens, E Cadoni, L Tack, A Madder - Molecules, 2022 - mdpi.com
Singlet oxygen (1O2) is the excited state of ground, triplet state, molecular oxygen (O2).
Photosensitized 1O2 has been extensively studied as one of the reactive oxygen species …

[HTML][HTML] pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma

Y Huang, H Lai, J Jiang, X Xu, Z Zeng, L Ren… - Asian journal of …, 2022 - Elsevier
Photodynamic therapy (PDT)-mediated oxidation treatment is extremely attractive for skin
melanoma ablation, but the strong hydrophobicity and poor tumor selectivity of …

Exploiting directed self-assembly and disassembly for off-to-on fluorescence responsive live cell imaging

N Curtin, M Garre, JB Bodin, N Solem… - RSC …, 2022 - pubs.rsc.org
A bio-responsive nanoparticle was formed by the directed self-assembly (DSA) of a
hydrophobic NIR-fluorophore with poloxamer P188. Fluorophore emission was switched off …

Synthesis and Photodynamic Activities of Pyridine-or Pyridinium-Substituted Aza-BODIPY Photosensitizers

C Liu, C Liu, X Ji, W Zhao, X Dong - Journal of Medicinal …, 2024 - ACS Publications
In this work, various novel pyridinyl-and pyridinium-modified Aza-BODIPY PSs were
designed and constructed based on monoiodo Aza-BODIPY PSs (BDP-4 and BDP-15) in an …

Aza-BODIPY photosensitizer substituted with phthalonitrile groups: Synthesis, photophysical properties and in vitro tests for breast cancer

Ş Özçelik, AG Yurttaş, MU Kahveci, AM Sevim… - Journal of Molecular …, 2023 - Elsevier
In photodynamic therapy (PDT), reactive oxygen species (ROS) are generated through
dynamic interactions between light of a specific wavelength, a photosensitizer (PS) and …

Effect of morpholine and charge distribution of cyanine dyes on cell internalization and cytotoxicity

S Wangngae, K Chansaenpak, O Weeranantanapan… - Scientific Reports, 2022 - nature.com
To improve the potency of Heptamethine cyanines (Hcyanines) in cancer research, we
designed and synthesized two novel Hcyanines based theranostic probes, IR794-Morph …

Aza-BODIPY encapsulated polymeric nanoparticles as an effective nanodelivery system for photodynamic cancer treatment

J Treekoon, K Chansaenpak, G Tumcharern… - Materials Chemistry …, 2021 - pubs.rsc.org
Polymeric nanoparticles represent an emerging technology in the field of theranostic
nanomedicine that combines diagnostic and therapeutic applications in a single agent. In …

Aza-BODIPY-based fluorescent and colorimetric sensors and probes

Ö Sonkaya, C Soylukan, M Pamuk Algi… - Current Organic …, 2023 - ingentaconnect.com
Aza-boron-dipyrromethenes (Aza-BODIPYs) represent an important class of chromophores
absorbing and emitting in the near-infrared (NIR) region. They have unique optical and …

Evaluation of Nanoparticles Covalently Bound with BODIPY for Their Photodynamic Therapy Applicability

MC Malacarne, E Caruso, MB Gariboldi… - International Journal of …, 2024 - mdpi.com
Photodynamic therapy (PDT) relies on the combined action of a photosensitizer (PS), light at
an appropriate wavelength, and oxygen, to produce reactive oxygen species (ROS) that …

Recent advances in lipid-based nanovesicular delivery systems for melanoma therapy

M Kurakula, L Chen, AK Tiwari… - Critical Reviews™ in …, 2021 - dl.begellhouse.com
Melanoma is one of the most aggressive forms of cancer with limited treatment options
available. Successful treatment involves a combination of surgical resection of the tumor; …