Endolichenic Fungi: A Promising Medicinal Microbial Resource to Discover Bioactive Natural Molecules—An Update

W Zhang, Q Ran, H Li, H Lou - Journal of Fungi, 2024 - mdpi.com
Lichens are some of the most unique fungi and are naturally encountered as symbiotic
biological organisms that usually consist of fungal partners (mycobionts) and photosynthetic …

The basic leucine zipper domain (bZIP) transcription factor BbYap1 promotes evasion of host humoral immunity and regulates lipid homeostasis contributing to fungal virulence …

G Wang, B Chen, X Zhang, G Du, G Han, J Liu, Y Peng - Msphere, 2024 - journals.asm.org
Basic leucine zipper domain transcription factors (TFs), of which yeast activator protein (Yap)
is a significant class, are crucial for the development of sclerotia, the stress response …

TDO2 inhibition counters Benzo [a] pyrene-induced immune evasion and suppresses tumorigenesis in lung adenocarcinoma

İ Taş, M Varlı, S Pulat, HB Sim, JJ Kim, H Kim - Cancer & Metabolism, 2024 - Springer
Abstract Introduction Benzo [a] pyrene (BaP) is a toxic polycyclic aromatic hydrocarbon
known as an exogenous AhR ligand. This study investigates the role of BaP in inducing …

[HTML][HTML] Unveiling the antimetastatic activity of monoterpene indole alkaloids targeting MMP9 in cancer cells, with a focus on pharmacokinetic and cellular insights

M Varlı, K Lee, KB Kang, H Kim - Molecules and Cells, 2024 - Elsevier
Distant metastasis, together with acquired resistance, limits the therapeutic impact of
chemotherapy and molecularly targeted therapies. The properties of the tumor …

Bioprospecção de atividades biológicas do Rhizopus sp.

VMS LEITÃO - 2024 - tedebc.ufma.br
Introdução: Os fungos têm sido reconhecidos como uma grande fonte de metabólitos
bioativos com grande aplicabilidade médica e farmacêutica. O Rhizopus sp possui …