Osteosarcoma is the most common primary bone cancer in children and young adults.
Limited progress has been made in improving the survival outcomes in patients with …

Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …

Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …

Mesenchymal stem cells (MSC) are multipotent stromal cells with the potential to
differentiate into several cell types. MSC‐based therapy has emerged as a promising …

Osteosarcoma is a primary malignant tumor that tends to threaten children and adolescents,
and the 5-year event-free survival rate has not improved significantly in the past three …

Mesenchymal stem/stromal cells (MSCs) have an immunoregulatory capacity and have
been used in different clinical protocols requiring control of the immune response. However …

Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …

Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to
be popular based on progressive accumulation of preclinical mechanistic evidence. This …