[HTML][HTML] Control of protein synthesis in yeast mitochondria: the concept of translational activators

JM Herrmann, MW Woellhaf, N Bonnefoy - Biochimica et Biophysica Acta …, 2013 - Elsevier
Mitochondria contain their own genome which codes for a small number of proteins. Most
mitochondrial translation products are part of the membrane-embedded reaction centers of …

Schizosaccharomyces pombe as a fundamental model for research on mitochondrial gene expression: Progress, achievements and outlooks

N Dinh, N Bonnefoy - IUBMB life, 2024 - Wiley Online Library
Schizosaccharomyces pombe (fission yeast) is an attractive model for mitochondrial
research. The organism resembles human cells in terms of mitochondrial inheritance …

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

DU Kim, J Hayles, D Kim, V Wood, HO Park… - Nature …, 2010 - nature.com
We report the construction and analysis of 4,836 heterozygous diploid deletion mutants
covering 98.4% of the fission yeast genome providing a tool for studying eukaryotic biology …

Designing phage cocktails to combat the emergence of bacteriophage-resistant mutants in multidrug-resistant Klebsiella pneumoniae

S Yoo, KM Lee, N Kim, TN Vu, R Abadie… - Microbiology …, 2024 - Am Soc Microbiol
Phage therapy, an emerging strategy in the fight against recalcitrant bacterial infections,
encounters a significant hurdle posed by the development of phage-resistant bacterial …

[HTML][HTML] Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs

JAM Smeitink, O Elpeleg, H Antonicka… - The American Journal of …, 2006 - cell.com
The 13 polypeptides encoded in mitochondrial DNA (mtDNA) are synthesized in the
mitochondrial matrix on a dedicated protein-translation apparatus that resembles that found …

[HTML][HTML] Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast

T Fukuda, Y Ebi, T Saigusa, K Furukawa, S Yamashita… - Elife, 2020 - elifesciences.org
Degradation of mitochondria through mitophagy contributes to the maintenance of
mitochondrial function. In this study, we identified that Atg43, a mitochondrial outer …

[HTML][HTML] mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG

HR Soleimanpour-Lichaei, I Kühl, M Gaisne, JF Passos… - Molecular cell, 2007 - cell.com
Human mitochondria contain their own genome, encoding 13 polypeptides that are
synthesized within the organelle. The molecular processes that govern and facilitate this …

The human mitochondrial ribosome recycling factor is essential for cell viability

J Rorbach, R Richter, HJ Wessels, M Wydro… - Nucleic acids …, 2008 - academic.oup.com
The molecular mechanism of human mitochondrial translation has yet to be fully described.
We are particularly interested in understanding the process of translational termination and …

Potential biomarkers for ischemic heart damage identified in mitochondrial proteins by comparative proteomics

N Kim, Y Lee, H Kim, H Joo, JB Youm, WS Park… - …, 2006 - Wiley Online Library
We used proteomics to detect regional differences in protein expression levels from
mitochondrial fractions of control, ischemia–reperfusion (IR), and ischemic preconditioned …

Translational activators and mitoribosomal isoforms cooperate to mediate mRNA-specific translation in Schizosaccharomyces pombe mitochondria

CJ Herbert, S Labarre-Mariotte, D Cornu… - Nucleic Acids …, 2021 - academic.oup.com
Mitochondrial mRNAs encode key subunits of the oxidative phosphorylation complexes that
produce energy for the cell. In Saccharomyces cerevisiae, mitochondrial translation is under …