Stiffness sensing by cells
PA Janmey, DA Fletcher… - Physiological …, 2020 - journals.physiology.org
Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …
signals are important elements in normal tissue development as well as in disease initiation …
PDMS with designer functionalities—Properties, modifications strategies, and applications
Rapid progress in micro-and nanotechnologies such as lab-on-a-chip (microfluidic
networks, sensors, actuators, and connectors), soft lithography (replica moulding …
networks, sensors, actuators, and connectors), soft lithography (replica moulding …
Development of polydimethylsiloxane substrates with tunable elastic modulus to study cell mechanobiology in muscle and nerve
Mechanics is an important component in the regulation of cell shape, proliferation, migration
and differentiation during normal homeostasis and disease states. Biomaterials that match …
and differentiation during normal homeostasis and disease states. Biomaterials that match …
Engineering microscale topographies to control the cell–substrate interface
Cells in their in vivo microenvironment constantly encounter and respond to a multitude of
signals. While the role of biochemical signals has long been appreciated, the importance of …
signals. While the role of biochemical signals has long been appreciated, the importance of …
Matrix nanotopography as a regulator of cell function
DH Kim, PP Provenzano, CL Smith… - Journal of Cell …, 2012 - rupress.org
The architecture of the extracellular matrix (ECM) directs cell behavior by providing spatial
and mechanical cues to which cells respond. In addition to soluble chemical factors …
and mechanical cues to which cells respond. In addition to soluble chemical factors …
Engineering substrate topography at the micro‐and nanoscale to control cell function
CJ Bettinger, R Langer… - Angewandte Chemie …, 2009 - Wiley Online Library
The interaction of mammalian cells with nanoscale topography has proven to be an
important signaling modality in controlling cell function. Naturally occurring nanotopographic …
important signaling modality in controlling cell function. Naturally occurring nanotopographic …
[HTML][HTML] Biophysical regulation of cell behavior—cross talk between substrate stiffness and nanotopography
The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …
influence numerous developmental, physiological, and pathological processes in vivo …
Modulation of cell adhesion, proliferation and differentiation on materials designed for body implants
L Bacakova, E Filova, M Parizek, T Ruml… - Biotechnology …, 2011 - Elsevier
The interaction of cells and tissues with artificial materials designed for applications in
biotechnologies and in medicine is governed by the physical and chemical properties of the …
biotechnologies and in medicine is governed by the physical and chemical properties of the …
Highly permeable skin patch with conductive hierarchical architectures inspired by amphibians and octopi for omnidirectionally enhanced wet adhesion
Amphibian adhesion systems can enhance adhesion forces on wet or rough surfaces via
hexagonal architectures, enabling omnidirectional peel resistance and drainage against wet …
hexagonal architectures, enabling omnidirectional peel resistance and drainage against wet …
Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells
The growth of stem cells can be modulated by physical factors such as extracellular matrix
nanotopography. We hypothesize that nanotopography modulates cell behavior by …
nanotopography. We hypothesize that nanotopography modulates cell behavior by …