What is polypharmacy? A systematic review of definitions

N Masnoon, S Shakib, L Kalisch-Ellett, GE Caughey - BMC geriatrics, 2017 - Springer
Background Multimorbidity and the associated use of multiple medicines (polypharmacy), is
common in the older population. Despite this, there is no consensus definition for …

An overview of prevalence, determinants and health outcomes of polypharmacy

M Khezrian, CJ McNeil, AD Murray… - … advances in drug …, 2020 - journals.sagepub.com
A high rate of polypharmacy is, in part, a consequence of the increasing proportion of
multimorbidity in the ageing population worldwide. Our understanding of the potential harm …

Clinical consequences of polypharmacy in elderly

RL Maher, J Hanlon, ER Hajjar - Expert opinion on drug safety, 2014 - Taylor & Francis
Introduction: Polypharmacy, defined as the use of multiple drugs or more than are medically
necessary, is a growing concern for older adults. MEDLINE and EMBASE databases were …

Association between polypharmacy and death: a systematic review and meta-analysis

N Leelakanok, AL Holcombe, BC Lund, X Gu… - Journal of the American …, 2017 - Elsevier
Objective Polypharmacy has been linked to a myriad of adverse consequences, and
escalating rates of polypharmacy present an emerging concern, particularly among older …

Polypharmacy definition and prevalence in heart failure: a systematic review

J Beezer, M Al Hatrushi, A Husband, A Kurdi… - Heart failure …, 2022 - Springer
Polypharmacy and heart failure are becoming increasingly common due to an ageing
population and the rise of multimorbidity. Treating heart failure necessitates prescribing of …

Polypharmacy, adverse drug reactions, and geriatric syndromes

BM Shah, ER Hajjar - Clinics in geriatric medicine, 2012 - geriatric.theclinics.com
The older population, composed of adults aged 65 years or older, is the fastest growing
segment of the United States population. The Administration of Aging of the United States …

Medication non-adherence among elderly patients newly discharged and receiving polypharmacy

L Pasina, AL Brucato, C Falcone, E Cucchi, A Bresciani… - Drugs & aging, 2014 - Springer
Background Poor adherence may have a major impact on clinical outcome, contributing to
substantial worsening of disease, increased health care costs and even death. With …

Adverse drug reactions in hospitalized patients: results of the FORWARD (Facilitation of Reporting in Hospital Ward) study

C Giardina, PM Cutroneo, E Mocciaro… - Frontiers in …, 2018 - frontiersin.org
Background: Adverse drug reactions (ADRs) are an important public health problem,
representing a major cause of morbidity and mortality. However, several countries have no …

Multiple diseases and polypharmacy in the elderly: challenges for the internist of the third millennium

A Nobili, S Garattini, PM Mannucci - Journal of comorbidity, 2011 - journals.sagepub.com
The pattern of patients admitted to internal medicine wards has dramatically changed in the
last 20–30 years. Elderly people are now the most rapidly growing proportion of the patient …

Prevalence of polypharmacy in a Scottish primary care population

RA Payne, AJ Avery, M Duerden, CL Saunders… - European journal of …, 2014 - Springer
Purpose Polypharmacy—the use of multiple medications by a single patient—is an
important issue associated with various adverse clinical outcomes and rising costs. It is also …