Biomarkers of diabetic kidney disease

HM Colhoun, ML Marcovecchio - Diabetologia, 2018 - Springer
Diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in
diabetes. The quest for both prognostic and surrogate endpoint biomarkers for advanced …

Emerging biomarkers for early detection of chronic kidney disease

M Mizdrak, M Kumrić, TT Kurir, J Božić - Journal of personalized …, 2022 - mdpi.com
Chronic kidney disease (CKD) is a major and serious global health problem that leads to
kidney damage as well as multiple systemic diseases. Early diagnosis and treatment are two …

Progression after AKI: understanding maladaptive repair processes to predict and identify therapeutic treatments

DP Basile, JV Bonventre, R Mehta… - Journal of the …, 2016 - journals.lww.com
Recent clinical studies indicate a strong link between AKI and progression of CKD. The
increasing prevalence of AKI must compel the nephrology community to consider the long …

Research progress on mechanism of podocyte depletion in diabetic nephropathy

H Dai, Q Liu, B Liu - Journal of diabetes research, 2017 - Wiley Online Library
Diabetic nephropathy (DN) together with glomerular hyperfiltration has been implicated in
the development of diabetic microangiopathy in the initial stage of diabetic diseases …

Stem cell-derived and circulating exosomal microRNAs as new potential tools for diabetic nephropathy management

L Peng, Y Chen, S Shi, H Wen - Stem Cell Research & Therapy, 2022 - Springer
Background Despite major advances in the treatment of diabetic nephropathy (DN) in recent
years, it remains the most common cause of end-stage renal disease. An early diagnosis …

Biomarkers of diabetic nephropathy: A 2017 update

N Papadopoulou-Marketou… - Critical reviews in …, 2017 - Taylor & Francis
Diabetic nephropathy (DN), also named diabetic kidney disease (DKD), is a devastating
complication in patients with both type 1 and 2 diabetes mellitus (T1D and T2D) and its …

A comprehensive analysis and annotation of human normal urinary proteome

M Zhao, M Li, Y Yang, Z Guo, Y Sun, C Shao, M Li… - Scientific reports, 2017 - nature.com
Biomarkers are measurable changes associated with the disease. Urine can reflect the
changes of the body while blood is under control of the homeostatic mechanisms; thus, urine …

Urinary biomarkers in the assessment of early diabetic nephropathy

C Gluhovschi, G Gluhovschi, L Petrica… - Journal of diabetes …, 2016 - Wiley Online Library
Diabetic nephropathy (DN) is a frequent and severe complication of diabetes mellitus (DM).
Its diagnosis in incipient stages may allow prompt interventions and an improved prognosis …

[HTML][HTML] Diabetic kidney disease, endothelial damage, and podocyte-endothelial crosstalk

CL Gil, E Hooker, B Larrivée - Kidney Medicine, 2021 - Elsevier
Diabetes-related complications are a significant source of morbidity and mortality worldwide.
Diabetic kidney disease is a frequent microvascular complication and a primary cause of …

Macrophages directly mediate diabetic renal injury

H You, T Gao, TK Cooper… - American Journal of …, 2013 - journals.physiology.org
Monocyte/macrophage recruitment correlates strongly with the progression of renal
impairment in diabetic nephropathy (DN), yet their direct role is not clear. We hypothesized …