Rheumatoid arthritis (RA) is an autoimmune disease affecting∼ 1% of the general
population. This disease is characterized by persistent articular inflammation and joint …

Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation
in joints, associated with synovial hyperplasia and with bone and cartilage destruction …

Dendritic cells (DCs) are the key professional antigen-presenting cells which bridge innate
and adaptive immune responses, inducing the priming and differentiation of naive to effector …

Nuclear factor-κB (NF-κB) is an inducible transcription factor controlled by two principal
signaling cascades, each activated by a set of signal ligands: the classical/canonical NF-κB …

Dopamine (DA) is a neurotransmitter in the central nervous system as well as in peripheral
tissues. Emerging evidence however points to DA also as a key transmitter between the …

Disease-modifying drugs have improved the treatment for autoimmune joint disorders, such
as rheumatoid arthritis, but inflammatory flares are a common experience. This work reports …

Rheumatoid arthritis (RA) is a chronic inflammatory syndrome designated by synovial joint
inflammation leading to cartilage degradation and bone damage as well as progressive …

Dendritic cells are professional antigen-presenting cells that maintain immune tolerance to
self-antigens by deleting or controlling the pathogenicity of auto-reactive T-cells. Dendritic …

Rheumatoid arthritis (RA) is a chronic, prevalent, immune-mediated, inflammatory, joint
disorder affecting millions of people worldwide. Despite current treatment options, many …