Mismatched (non-Watson–Crick) base pairs represent the most common type of DNA
damage, as they are permanently formed in living cells due to erroneous insertion, deletion …

Conditions of double-stranded DNA precipitation by the polyamines spermidine and
spermine have been determined experimentally and compared to theoretical predictions …

G-quadruplexes are nucleic acid secondary structures for which many biological roles have
been proposed but whose existence in vivo has remained elusive. To assess their formation …

DNA targeting drugs represent a large proportion of the actual anticancer drug
pharmacopeia, both in terms of drug brands and prescription volumes. Small DNA …

Here, we report a series of four novel Cu complexes, namely 2-(piperidin-1-ylmethyl)
quinoline copper (II) nitrate,[LACu (NO3) 2](Cu1), 4-(quinolin-2-ylmethyl) morpholine copper …

The reactivation of telomerase activity in most cancer cells supports the concept that
telomerase is a relevant target in oncology, and telomerase inhibitors have been proposed …

An efficient and facile one-step synthesis of highly substituted thiophenes - ScienceDirect Skip
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The macrocyclic bisacridine (CBA) has been reported previously to specifically recognize
single-stranded nucleic acid structures, especially DNA hairpins. The binding of the drug …

The acyclic bis-phenanthridinium ligands, and the cyclic analogue bind to ss-RNA by bis-
intercalation. Due to it's shorter linker exhibits mono-intercalative binding to ds …

The 9-aminoacridines play an important role in medicine. They were applied first in a
treatment of protozoal infections in the beginning of the last century. Recently, it has been …